{"id":"benzethonium","rwe":[{"pmid":"41728368","year":"2025","title":"Antimicrobial functional ingredients used in hand hygiene products: a cross-sectional survey on regional e-commerce platforms in Wuhan area of China.","finding":"","journal":"Asian biomedicine : research, reviews and news","studyType":"Clinical Study"},{"pmid":"41634981","year":"2026","title":"Calcium Dobesilate Interference in Two Urinary Total Protein Detection Methods.","finding":"","journal":"Journal of clinical laboratory analysis","studyType":"Clinical Study"},{"pmid":"41571075","year":"2026","title":"Distinct influence of preservatives on microbial community and resistance gene in bio-carriers biofilm and microplastics biofilm as revealed in sulfur autotrophic denitrification coupled with anammox system.","finding":"","journal":"Environmental research","studyType":"Clinical Study"},{"pmid":"41570760","year":"2026","title":"Spatiotemporal distribution of mass flows of quaternary ammonium compounds in Japanese rivers.","finding":"","journal":"The Science of the total environment","studyType":"Clinical Study"},{"pmid":"41558281","year":"2026","title":"Structural determinants of oxygenated benzalkonium-like disinfectants as human and rat 5α-reductase 1 inhibitors: Integrated SPR binding analysis with docking.","finding":"","journal":"Ecotoxicology and environmental safety","studyType":"Clinical Study"}],"_fda":{"id":"409680e7-1767-f9ac-e063-6394a90a0ed5","set_id":"036fd504-0cda-60ab-e063-6394a90a2f18","openfda":{"unii":["PH41D05744","ZEC193879Q"],"route":["TOPICAL"],"spl_id":["409680e7-1767-f9ac-e063-6394a90a0ed5"],"brand_name":["Liquid Bandage"],"spl_set_id":["036fd504-0cda-60ab-e063-6394a90a2f18"],"package_ndc":["79481-0606-1"],"product_ndc":["79481-0606"],"generic_name":["BENZETHONIUM CHLORIDE PLUS DYCLONINE HYDROCHLORIDE"],"product_type":["HUMAN OTC DRUG"],"substance_name":["BENZETHONIUM CHLORIDE","DYCLONINE HYDROCHLORIDE"],"manufacturer_name":["Meijer Distribution Inc"],"application_number":["M003"],"is_original_packager":[true]},"purpose":["Purpose First aid antiseptic Topical analgesic"],"version":"5","stop_use":["Stop use and ask a doctor if conditions persists or gets worse infection occurs symptoms persist for than 7 days or clear up and occur again within a few days"],"warnings":["Warnings For external use only. Flammable: Keep away from fire or flame. Do not use in the eyes over large areas of the body longer than 1 week unless directed by a doctor Ask a doctor before use if you have deep or puncture wounds animal bites serious burns Stop use and ask a doctor if conditions persists or gets worse infection occurs symptoms persist for than 7 days or clear up and occur again within a few days Keep out of reach of children. If swallowed, get medical help or call a Poison Control Center right away."],"questions":["Questions Call 1-866-964-0939"],"ask_doctor":["Ask a doctor before use if you have deep or puncture wounds animal bites serious burns"],"do_not_use":["Do not use in the eyes over large areas of the body longer than 1 week unless directed by a doctor"],"effective_time":"20251007","active_ingredient":["Active ingredients Benzethonium chloride 0.2% Dyclonine hydrochloride 0.75%"],"inactive_ingredient":["Inactive ingredients acetone, amyl acetate, castor oil, ethyl acetate, nitrocellulose, SD slcohol 40"],"indications_and_usage":["Uses first aid to prevent bacterial contamination in minor cuts, scrapes and burns for the temporary relief of pain in minor cuts, scrapes, and burns"],"safe_handling_warning":["Flammable: Keep away from fire or flame."],"other_safety_information":["Other information cap bottle tightly wipe top of bottle clean after each use store between 20° to 25°C (68° to 77°F) may temporarily sting upon application to remove, apply more Liquid Bandage and quickly wipe off do not allow to come into contact with fabrics, floors, counterops or other surfaces -- will stain."],"dosage_and_administration":["Directions for adults and children 2 years of age and older clean affected area apply a small amount on the area 1 to 3 times daily and let dry may be covered with a sterile bandage if bandaged, let dry first children under under 2 years of age; do not sure, consult a doctor"],"spl_product_data_elements":["Liquid Bandage Benzethonium chloride Plus Dyclonine hydrochloride ACETONE AMYL ACETATE CASTOR OIL ETHYL ACETATE PYROXYLIN ALCOHOL BENZETHONIUM CHLORIDE BENZETHONIUM DYCLONINE HYDROCHLORIDE DYCLONINE"],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, get medical help or call a Poison Control Center right away."],"package_label_principal_display_panel":["Principal Display Panel MEIJER For small cuts & wounds liquid bandage BENZETHONIUM CHLORIDE 0.2%/FIRST AID ANTISEPTIC DYCLONINE HYDROCHLORIDE 0.75%/TOPICAL ANALGESIC KILLS 99.9% OF GERMS TO HELP PREVENT INFECTION ​NET 0.3 FL OZ (9mL) image 1"]},"tags":[{"label":"benzethonium","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Muscarinic acetylcholine receptor M4","category":"target"},{"label":"CHRM4","category":"gene"},{"label":"HTR2A","category":"gene"},{"label":"CHRM3","category":"gene"},{"label":"D08AJ08","category":"atc"},{"label":"Topical","category":"route"},{"label":"Aerosol","category":"form"},{"label":"Active","category":"status"},{"label":"Itching of skin","category":"indication"},{"label":"Minor Skin Wound Pain","category":"indication"},{"label":"Prevent Minor Bacterial Skin Infection","category":"indication"},{"label":"Skin 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