{"id":"benexate","rwe":[],"tags":[{"label":"benexate","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["benexate hydrochloride","benexate","benexate HCl"],"offLabel":[],"synonyms":["benexate hydrochloride","benexate","benexate HCl"],"timeline":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"benexate","explanation":"Think of it like a fire extinguisher for your stomach. Benexate helps reduce the amount of acid produced in the stomach, which can help alleviate symptoms of conditions like heartburn and acid reflux. This can make it easier to digest food and reduce discomfort.","oneSentence":"Benexate works by inhibiting gastric acid secretion, but the exact mechanism of action is not well understood.","technicalDetail":"Benexate is believed to act as a selective inhibitor of gastric H+/K+ ATPase, the enzyme responsible for acid secretion in the parietal cells of the stomach."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3015","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=BENEXATE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:50:41.355559","biosimilars":[],"competitors":[],"genericName":"benexate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"010962","UNII":"O3PR2X907M","CHEBI":"CHEBI:31258","INN_ID":"6067","UMLSCUI":"C0208925","ChEMBL_ID":"CHEMBL2104696","KEGG_DRUG":"D07506","PUBCHEM_CID":"2316","SECONDARY_CAS_RN":"78718-52-2","MESH_SUPPLEMENTAL_RECORD_UI":"C057164"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":7,"therapeuticAreas":["Cardiovascular"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"BENEXATE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Benexate is a small molecule drug in the benexate class, but specific details about its target, indications, and pharmacokinetics are unknown. Its commercial status, including patent status and generic availability, is also unclear. As a result, it is difficult to provide a comprehensive summary of benexate's clinical use and safety profile. Further research is needed to determine its potential therapeutic applications and key safety considerations. Without more information, it is challenging to assess benexate's place in modern pharmacotherapy.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}