{"id":"bemetizide","rwe":[],"tags":[{"label":"bemetizide","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"bemeticide","offLabel":[],"synonyms":["bemetizide","bemeticide","dehydrosanol"],"timeline":[],"brandName":"Bemeticide","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"bemetizide","explanation":"Imagine your cells have special channels that let certain substances in and out. Bemetizide is a small molecule that can fit into these channels and change how they work, which can affect the balance of substances inside and outside the cell.","oneSentence":"Bemetizide is thought to work by modulating ion transport across cell membranes.","technicalDetail":"Bemetizide is a small molecule that acts as a potassium-sparing diuretic, potentially inhibiting the sodium-potassium-chloride cotransporter (NKCC2) or other ion transporters to increase potassium levels and reduce sodium reabsorption in the kidneys."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/297","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=BEMETIZIDE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:55:25.860904","biosimilars":[],"competitors":[],"genericName":"bemetizide","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"007089","UNII":"EZN4D2O31B","CHEBI":"CHEBI:135640","INN_ID":"3205","RXNORM":"22427","UMLSCUI":"C0057293","ChEMBL_ID":"CHEMBL2104003","PUBCHEM_CID":"72070","MESH_SUPPLEMENTAL_RECORD_UI":"C010100"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Nephrology"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Bemeticide is a small molecule with synonyms including BEMETIZIDA, BEMETIZIDE, and DEHYDROSANOL. Its modality is classified as a small molecule.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}