{"id":"bci-540","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Dizziness"},{"rate":"10-20%","effect":"Headache"},{"rate":"5-10%","effect":"Nausea"}]},"_chembl":{"chemblId":"CHEMBL5678794","moleculeType":null,"molecularWeight":"340.22"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"BCI-540 acts as a positive allosteric modulator of GABA_A receptors, enhancing the inhibitory effects of GABA. This mechanism is thought to contribute to its potential therapeutic effects in various neurological disorders.","oneSentence":"BCI-540 is a small molecule that modulates the activity of GABA_A receptors.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:22:25.845Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Major depressive disorder"},{"name":"Generalized anxiety disorder"}]},"trialDetails":[{"nctId":"NCT00621270","phase":"PHASE2","title":"Safety and Effectiveness Study of BCI-540 Versus Placebo in the Treatment of Major Depressive Disorder With Concomitant Anxiety","status":"COMPLETED","sponsor":"BrainCells Inc.","startDate":"2008-01","conditions":"Major Depressive Disorder, Anxiety","enrollment":115}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"BCI-540","genericName":"BCI-540","companyName":"BrainCells Inc.","companyId":"braincells-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"BCI-540 is a small molecule that modulates the activity of GABA_A receptors. Used for Major depressive disorder, Generalized anxiety disorder.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}