{"id":"basic-buccal-procedure-long-acting-local","safety":{"commonSideEffects":[{"rate":null,"effect":"Local tissue irritation"},{"rate":null,"effect":"Allergic reaction to local anesthetic"},{"rate":null,"effect":"Numbness or paresthesia"}]},"_chembl":{"chemblId":"CHEMBL4303311","moleculeType":"Small molecule","molecularWeight":"301.39"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This appears to be a procedural intervention rather than a traditional pharmaceutical drug, combining a basic buccal (cheek/mouth) procedure with a long-acting local anesthetic formulation to extend the duration of local pain control or therapeutic benefit. The long-acting component likely uses a sustained-release or depot formulation of a local anesthetic agent administered at the buccal site.","oneSentence":"A buccal procedure combined with long-acting local anesthetic delivery to provide sustained pain relief or therapeutic effect in the oral cavity.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:03:28.978Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Buccal pain management or local therapeutic delivery (specific indication unclear from description)"}]},"trialDetails":[{"nctId":"NCT05300685","phase":"PHASE3","title":"Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty","status":"RECRUITING","sponsor":"University of California, San Francisco","startDate":"2022-02-15","conditions":"Urethral Stricture, Male","enrollment":60}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Basic buccal procedure + Long acting local","genericName":"Basic buccal procedure + Long acting local","companyName":"University of California, San Francisco","companyId":"university-of-california-san-francisco","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A buccal procedure combined with long-acting local anesthetic delivery to provide sustained pain relief or therapeutic effect in the oral cavity. Used for Buccal pain management or local therapeutic delivery (specific indication unclear from description).","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}