{"id":"baminercept-alfa-3","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Injection site reactions"},{"rate":"10-20%","effect":"Fatigue"},{"rate":"10-20%","effect":"Headache"}]},"_chembl":{"chemblId":"CHEMBL1742988","moleculeType":"Protein"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Baminercept alfa 3 works by binding to and inhibiting the activity of TGF-beta superfamily members, which play a key role in the pathogenesis of various diseases. This inhibition can lead to a reduction in inflammation and fibrosis, and may have therapeutic benefits in conditions such as fibrosis and cancer. However, the exact mechanism of action of baminercept alfa 3 is complex and not fully understood.","oneSentence":"Baminercept alfa 3 is a fusion protein that targets and modulates the activity of TGF-beta superfamily members.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T03:57:47.891Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Idiopathic pulmonary fibrosis"}]},"trialDetails":[{"nctId":"NCT00664573","phase":"PHASE2","title":"104RA204 Assessment of the Safety and Efficacy of BG9924 in Rheumatoid Arthritis (RA) Participants","status":"TERMINATED","sponsor":"Biogen","startDate":"2007-11","conditions":"Rheumatoid Arthritis","enrollment":339},{"nctId":"NCT00664716","phase":"PHASE2","title":"Assessment Of The Safety And Efficacy Of BG9924 In Rheumatoid Arthritis (RA) Participants","status":"COMPLETED","sponsor":"Biogen","startDate":"2007-07","conditions":"Rheumatoid Arthritis","enrollment":391}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["BG9924","LT beta"],"phase":"phase_2","status":"active","brandName":"Baminercept alfa 3","genericName":"Baminercept alfa 3","companyName":"Biogen","companyId":"biogen","modality":"Biologic","firstApprovalDate":"","aiSummary":"Baminercept alfa 3 is a fusion protein that targets and modulates the activity of TGF-beta superfamily members. Used for Idiopathic pulmonary fibrosis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}