{"id":"bamifylline","rwe":[],"tags":[{"label":"bamifylline","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"R03DA08","category":"atc"},{"label":"Active","category":"status"},{"label":"Analgesics","category":"pharmacology"},{"label":"Anti-Asthmatic Agents","category":"pharmacology"},{"label":"Bronchodilator Agents","category":"pharmacology"},{"label":"Cardiovascular Agents","category":"pharmacology"},{"label":"Central Nervous System Agents","category":"pharmacology"},{"label":"Peripheral Nervous System Agents","category":"pharmacology"},{"label":"Respiratory System Agents","category":"pharmacology"},{"label":"Sensory System Agents","category":"pharmacology"},{"label":"Vasodilator Agents","category":"pharmacology"}],"phase":"phase_2","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"bamiphylline","offLabel":[],"synonyms":["bamifylline","bamiphylline","benzetamophylline","benzethamophylline"],"timeline":[],"brandName":"Bamiphylline","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"bamifylline","explanation":"Imagine your body's cells have a messaging system that helps them communicate with each other. Bamiphylline is believed to affect this system by influencing the way cells break down and reuse these messages, which can help regulate various bodily functions.","oneSentence":"Bamiphylline is thought to work by modulating phosphodiesterase activity, although the exact details of its mechanism are unclear.","technicalDetail":"Bamiphylline is a phosphodiesterase inhibitor, which means it blocks the action of enzymes that break down cyclic nucleotides, such as cAMP and cGMP. This can lead to increased levels of these molecules, which in turn can activate various cellular pathways and influence physiological responses."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/287","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=BAMIFYLLINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:49:23.219875","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T11:03:51.196803+00:00","fieldsConflicting":0,"overallConfidence":0.95},"biosimilars":[],"competitors":[{"drugName":"diprophylline","drugSlug":"diprophylline","fdaApproval":"1951-03-07","relationship":"same-class"},{"drugName":"choline theophyllinate","drugSlug":"choline-theophyllinate","fdaApproval":"1981-11-05","relationship":"same-class"},{"drugName":"theophylline","drugSlug":"theophylline","fdaApproval":"1940-04-19","genericCount":53,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"bamifylline","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"diprophylline","brandName":"diprophylline","genericName":"diprophylline","approvalYear":"1951","relationship":"same-class"},{"drugId":"choline-theophyllinate","brandName":"choline theophyllinate","genericName":"choline theophyllinate","approvalYear":"1981","relationship":"same-class"},{"drugId":"theophylline","brandName":"theophylline","genericName":"theophylline","approvalYear":"1940","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"005237","UNII":"ZTY15D026H","CHEBI":"CHEBI:135605","INN_ID":"1837","RXNORM":"18752","UMLSCUI":"C0052945","ChEMBL_ID":"CHEMBL2110760","KEGG_DRUG":"D07491","DRUGBANK_ID":"DB13203","PUBCHEM_CID":"16229","MESH_SUPPLEMENTAL_RECORD_UI":"C006683"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":42,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"R03DA08","allCodes":["R03DA08"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Bamiphylline is a small molecule with synonyms including AC-3810 FREE BASE, BAMIFILINA, BAMIFYLLINE, and BAX-2739Z FREE BASE.","enrichmentLevel":5,"visitCount":0,"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T11:03:51.196803+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}