{"id":"azithropycin-according-to-symptoms","safety":{"commonSideEffects":[{"rate":"5-10%","effect":"Gastrointestinal disturbance (nausea, diarrhea, abdominal pain)"},{"rate":"2-5%","effect":"Headache"},{"rate":"1-3%","effect":"Vaginitis"},{"rate":"rare","effect":"QT prolongation"},{"rate":"rare","effect":"Hepatotoxicity"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Azithromycin binds to the bacterial 23S rRNA component of the 50S ribosomal subunit, preventing peptide bond formation and elongation of the bacterial polypeptide chain. This results in bacteriostatic activity against a broad range of gram-positive and gram-negative bacteria, as well as some atypical organisms. The drug accumulates in tissues and has a long half-life, allowing for extended dosing intervals.","oneSentence":"Azithromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:28:04.913Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Bacterial infections including respiratory tract infections, otitis media, and skin infections"},{"name":"Atypical infections caused by Mycoplasma, Chlamydia, and Legionella species"},{"name":"Prophylaxis of Mycobacterium avium complex in immunocompromised patients"}]},"trialDetails":[{"nctId":"NCT04339270","phase":"PHASE4","title":"Chronic Airway Disease, Mucus Rheology and Exacerbations","status":"RECRUITING","sponsor":"University Hospital, Montpellier","startDate":"2023-02-03","conditions":"Chronic Obstructive Pulmonary Disease","enrollment":72}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Azithropycin according to symptoms","genericName":"Azithropycin according to symptoms","companyName":"University Hospital, Montpellier","companyId":"university-hospital-montpellier","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Azithromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. Used for Bacterial infections including respiratory tract infections, otitis media, and skin infections, Atypical infections caused by Mycoplasma, Chlamydia, and Legionella species, Prophylaxis of Mycobacterium avium complex in immunocompromised patients.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}