{"id":"azathioprine-aza","safety":{"commonSideEffects":[{"rate":"10-15","effect":"Bone marrow suppression (leukopenia, thrombocytopenia, anemia)"},{"rate":"10-12","effect":"Nausea and vomiting"},{"rate":"5-10","effect":"Hepatotoxicity"},{"rate":null,"effect":"Increased infection risk"},{"rate":"1-2","effect":"Pancreatitis"},{"rate":"5-8","effect":"Rash"}]},"_chembl":{"chemblId":"CHEMBL1542","moleculeType":"Small molecule","molecularWeight":"277.27"},"_dailymed":{"setId":"d288e484-32fc-4b46-b504-d75a0fac8663","title":"AZATHIOPRINE TABLET [PD-RX PHARMACEUTICALS, INC.]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Azathioprine acts as an immunosuppressant by interfering with nucleotide metabolism, particularly purine synthesis. After hepatic conversion to 6-mercaptopurine and further metabolism, it inhibits the proliferation of lymphocytes and reduces the production of antibodies and cell-mediated immune responses. 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