{"id":"azapetine","rwe":[],"tags":[{"label":"azapetine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"C04AX30","category":"atc"},{"label":"Active","category":"status"},{"label":"Peripheral vascular disease","category":"indication"}],"phase":"unknown","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"ilidar","offLabel":[],"synonyms":["azapetine","azapetine phosphate","peridil","Ro-2-3248","ilidar","ilidar phosphate"],"timeline":[],"brandName":"Ilidar","ecosystem":[{"indication":"Peripheral vascular disease","otherDrugs":[{"name":"papaverine","slug":"papaverine","company":""},{"name":"pentoxifylline","slug":"pentoxifylline","company":""},{"name":"phentolamine","slug":"phentolamine","company":"Novartis"},{"name":"ticagrelor","slug":"ticagrelor","company":"Astrazeneca Lp"}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","drugClass":"azapetine","explanation":"Think of platelets like tiny messengers in your blood that help your body form clots when you're injured. When platelets get too active, it can lead to problems like blood clots and poor circulation. Ilidar helps to calm down these platelets, making it easier for blood to flow and reducing the risk of complications.","oneSentence":"Ilidar works by inhibiting platelet aggregation, which helps to improve blood flow and reduce the risk of blood clots.","technicalDetail":"Ilidar exerts its effects by inhibiting the aggregation of platelets, likely through a mechanism involving the inhibition of platelet-activating factor (PAF) or other signaling pathways."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/265","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=azapetine","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:47:46.805599","biosimilars":[],"competitors":[{"drugName":"phenoxybenzamine","drugSlug":"phenoxybenzamine","fdaApproval":"1953-01-26","genericCount":6,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"azapetine","indications":{"approved":[{"name":"Peripheral vascular disease","source":"DrugCentral","snomedId":400047006,"regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"phenoxybenzamine","brandName":"phenoxybenzamine","genericName":"phenoxybenzamine","approvalYear":"1953","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"000701","UNII":"9TTR0UA2KC","CHEBI":"CHEBI:134955","UMLSCUI":"C0052752","ChEMBL_ID":"CHEMBL2110596","KEGG_DRUG":"D07178","DRUGBANK_ID":"DB13727","PUBCHEM_CID":"8966","SNOMEDCT_US":"30827002","SECONDARY_CAS_RN":"130-83-6","MESH_SUPPLEMENTAL_RECORD_UI":"C004448"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":37,"therapeuticAreas":["Hematology"],"atcClassification":{"source":"DrugCentral","atcCode":"C04AX30","allCodes":["C04AX30"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Ilidar (azapetine) is a small molecule drug in the azapetine class, used to treat peripheral vascular disease. Its exact mechanism of action is unknown, but it is believed to work by inhibiting platelet aggregation and improving blood flow. Ilidar's commercial status is unclear, and it may be patented or off-patent. As a pharmaceutical professional, it is essential to consider the potential risks and benefits of this medication, including any key safety considerations. Further research is needed to fully understand Ilidar's efficacy and safety profile.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}