{"id":"autologous-ucb-reinfusion","safety":{"commonSideEffects":[{"rate":null,"effect":"Infusion-related reactions"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Infection"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"This therapy involves collecting a patient's own umbilical cord blood stem cells (typically stored at birth) and reinfusing them to support hematopoietic and immunological recovery. The mechanism leverages the regenerative and immunomodulatory properties of cord blood-derived cells, including hematopoietic stem cells and other progenitors, to enhance immune function and potentially repair damaged tissues.","oneSentence":"Autologous umbilical cord blood (UCB) cells are reinfused into patients to promote immune reconstitution and tissue repair.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T02:29:44.381Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cerebral palsy (Phase 2)"},{"name":"Autism spectrum disorder (Phase 2)"}]},"trialDetails":[{"nctId":"NCT01147653","phase":"PHASE2","title":"A Randomized Study of Autologous Umbilical Cord Blood Reinfusion in Children With Cerebral Palsy","status":"COMPLETED","sponsor":"Joanne Kurtzberg, MD","startDate":"2010-06","conditions":"Cerebral Palsy, CP, Spastic Cerebral Palsy","enrollment":63}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":3,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Autologous UCB Reinfusion","genericName":"Autologous UCB Reinfusion","companyName":"Joanne Kurtzberg, MD","companyId":"joanne-kurtzberg-md","modality":"Biologic","firstApprovalDate":"","aiSummary":"Autologous umbilical cord blood (UCB) cells are reinfused into patients to promote immune reconstitution and tissue repair. Used for Cerebral palsy (Phase 2), Autism spectrum disorder (Phase 2).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}