{"id":"auriclosene-irrigation-solution-0-2","safety":{"commonSideEffects":[{"rate":"null","effect":"Skin irritation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Auriclosene works by binding to the bacterial cell membrane, causing leakage of essential ions and ultimately leading to cell death. This mechanism of action is effective against a broad spectrum of microorganisms, including bacteria and fungi. The solution is designed for irrigation and cleansing of wounds and other infected areas.","oneSentence":"Auriclosene Irrigation Solution is a topical antimicrobial agent that kills bacteria and fungi by disrupting their cell membranes.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:57:35.724Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of mild to moderate diabetic foot ulcers"}]},"trialDetails":[{"nctId":"NCT02130518","phase":"PHASE2","title":"Efficacy Study of Auriclosene Irrigation Solution on Urinary Catheter Patency","status":"UNKNOWN","sponsor":"NovaBay Pharmaceuticals, Inc.","startDate":"2014-09","conditions":"Urinary Catheter Blockage and Encrustation","enrollment":140}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Auriclosene Irrigation Solution, 0.2%","genericName":"Auriclosene Irrigation Solution, 0.2%","companyName":"NovaBay Pharmaceuticals, Inc.","companyId":"novabay-pharmaceuticals-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Auriclosene Irrigation Solution is a topical antimicrobial agent that kills bacteria and fungi by disrupting their cell membranes. Used for Treatment of mild to moderate diabetic foot ulcers.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}