{"id":"atr12-351","_chembl":null,"_dailymed":null,"_scrapedAt":"2026-03-28T05:38:47.070Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"_claudeStub":{"ts":1779123655,"model":"claude-sonnet-4-5-20250929"},"description":"ATR12-351 is an investigational therapeutic developed by Azitra Inc. currently in Phase 1 clinical development. Limited public information is available regarding its molecular target, mechanism of action, or specific therapeutic indications at this early stage of development.","indications":{"approved":[{"status":"investigational","condition":null,"patientPopulation":null}]},"trialDetails":[{"nctId":"NCT06137157","phase":"PHASE1","title":"Evaluation of Topical ATR12-351 in Adults With Netherton Syndrome","status":"RECRUITING","sponsor":"Azitra Inc.","startDate":"2024-06-19","conditions":"Netherton Syndrome","enrollment":12}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["ATR-12"],"phase":"phase_1","status":"active","brandName":"ATR12-351","genericName":"ATR12-351","companyName":"Azitra Inc.","companyId":"azitra-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"ATR12-351 is a small molecule being evaluated in a clinical study for the treatment of Netherton Syndrome. This study, NCT06137157, is a randomized, double-blind, vehicle-controlled, first-in-human safety, tolerability, and proof-of-concept study of topical ATR12-351 in adults with Netherton Syndrome.","enrichmentLevel":2,"visitCount":3,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":false,"indications":true,"safety":false,"trials":true,"score":2}}