{"id":"asu","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Diarrhea"},{"rate":null,"effect":"Abdominal discomfort"}]},"_chembl":null,"_dailymed":{"setId":"042817f9-675f-056a-e063-6394a90a2d97","title":"UNITED ASUTRA TC KIT COLGATE (SODIUM MONOFLUOROPHOSPHATE) KIT [PROCURALL SOLUTIONS]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"ASU is a mixture of unsaponifiable fractions derived from avocado and soybean oils that modulates inflammatory pathways, particularly reducing IL-6, IL-8, and TNF-α production. It inhibits matrix metalloproteinases and other enzymes responsible for cartilage breakdown, while promoting cartilage repair mechanisms. 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Osteoarthritis","enrollment":""}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":548,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"ASU","genericName":"ASU","companyName":"Laboratoires Expanscience S.A.","companyId":"laboratoires-expanscience-s-a","modality":"Small molecule","firstApprovalDate":"","aiSummary":"ASU (avocado-soybean unsaponifiables) is a plant extract that reduces inflammatory mediators and inhibits cartilage degradation in osteoarthritis. Used for Osteoarthritis of the knee and hip.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}