{"id":"assess-aaa-rupture-risk-by-pet-cta-scans","safety":{"commonSideEffects":[{"rate":null,"effect":"Radiation exposure from PET and CT imaging"},{"rate":null,"effect":"Contrast-related nephropathy (from CTA contrast agent)"},{"rate":null,"effect":"Allergic reaction to radiopharmaceutical or contrast"}]},"_chembl":{"chemblId":"CHEMBL1909342","moleculeType":"Small molecule","molecularWeight":"395.44"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"PET-CTA combines metabolic imaging (PET) with anatomical imaging (CTA) to evaluate both the structural dimensions of an abdominal aortic aneurysm and its metabolic activity, which may indicate inflammation and instability. This multimodal approach helps clinicians stratify rupture risk and guide treatment decisions, distinguishing stable from high-risk aneurysms that may require intervention.","oneSentence":"This is a diagnostic imaging protocol using PET-CTA (positron emission tomography combined with computed tomography angiography) to assess the risk of abdominal aortic aneurysm (AAA) rupture.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:42:42.824Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Risk stratification of abdominal aortic aneurysm (AAA) for rupture prediction"}]},"trialDetails":[{"nctId":"NCT03231397","phase":"PHASE4","title":"Predictors of AAA Expansion and/or Rupture","status":"TERMINATED","sponsor":"Washington University School of Medicine","startDate":"2017-08-01","conditions":"Abdominal Aortic Aneurysm (AAA)","enrollment":2}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Assess AAA rupture risk by PET-CTA scans","genericName":"Assess AAA rupture risk by PET-CTA scans","companyName":"Washington University School of Medicine","companyId":"washington-university-school-of-medicine","modality":"Small molecule","firstApprovalDate":"","aiSummary":"This is a diagnostic imaging protocol using PET-CTA (positron emission tomography combined with computed tomography angiography) to assess the risk of abdominal aortic aneurysm (AAA) rupture. Used for Risk stratification of abdominal aortic aneurysm (AAA) for rupture prediction.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}