{"id":"asf-1096-0-5-cream","safety":{"commonSideEffects":[{"rate":"unknown","effect":"Skin atrophy"},{"rate":"unknown","effect":"Hypersensitivity reactions"}]},"_chembl":{"chemblId":"CHEMBL5936290","moleculeType":null,"molecularWeight":"522.63"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It works by suppressing the immune system's response to inflammation, thereby reducing the symptoms associated with skin conditions such as eczema, psoriasis, and dermatitis. The exact mechanism of action involves the inhibition of phospholipase A2, which is involved in the production of inflammatory mediators.","oneSentence":"ASF 1096 0.5% cream is a topical corticosteroid used to reduce inflammation and itching in various skin conditions.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T04:10:59.255Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Eczema"},{"name":"Psoriasis"},{"name":"Dermatitis"}]},"trialDetails":[{"nctId":"NCT00625157","phase":"PHASE2","title":"Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions (2)","status":"COMPLETED","sponsor":"Astion Pharma A/S","startDate":"","conditions":"Discoid Lupus Erythematosus","enrollment":""},{"nctId":"NCT00625521","phase":"PHASE2","title":"Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions","status":"COMPLETED","sponsor":"Astion Pharma A/S","startDate":"2006-11","conditions":"Discoid Lupus Erythematosus","enrollment":32}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"ASF 1096 0.5 % cream","genericName":"ASF 1096 0.5 % cream","companyName":"Astion Pharma A/S","companyId":"astion-pharma-a-s","modality":"Small molecule","firstApprovalDate":"","aiSummary":"ASF 1096 0.5% cream is a topical corticosteroid used to reduce inflammation and itching in various skin conditions. Used for Eczema, Psoriasis, Dermatitis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}