{"id":"asc-enriched-lipofilling","safety":{"commonSideEffects":[{"rate":null,"effect":"Infection at harvest or injection site"},{"rate":null,"effect":"Hematoma or seroma"},{"rate":null,"effect":"Graft resorption"},{"rate":null,"effect":"Pain or discomfort at donor site"}]},"_chembl":{"chemblId":"CHEMBL1778796","moleculeType":"Small molecule","molecularWeight":"757.00"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The therapy enriches harvested autologous fat with adipose-derived stem cells, which are known to secrete growth factors and cytokines that enhance angiogenesis, reduce inflammation, and improve the viability and integration of transplanted adipose tissue. This cell-enriched approach aims to increase graft retention and functional outcomes compared to conventional lipofilling alone.","oneSentence":"ASC enriched lipofilling uses adipose-derived stem cells (ASCs) combined with autologous fat to promote tissue regeneration and improve graft survival in soft tissue augmentation.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:02:37.931Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Soft tissue augmentation and reconstruction"},{"name":"Lipodystrophy and contour deformities"}]},"trialDetails":[{"nctId":"NCT03258164","phase":"PHASE3","title":"Cosmetic Fat Transplantation Using Expanded ASC Enriched Fat Grafts","status":"COMPLETED","sponsor":"Stemform","startDate":"2017-03-22","conditions":"Breast Hypoplasia and Facial Ageing","enrollment":32}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":9,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"ASC enriched lipofilling","genericName":"ASC enriched lipofilling","companyName":"Stemform","companyId":"stemform","modality":"Biologic","firstApprovalDate":"","aiSummary":"ASC enriched lipofilling is a cosmetic fat transplantation procedure that has been studied for treating breast hypoplasia and facial ageing. It involves the use of expanded adipose-derived autologous mesenchymal stromal cells enriched in fat grafts, which is a small molecule modality.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}