{"id":"arsthinol","rwe":[{"pmid":"23831266","year":"2013","title":"The antitumor effects of an arsthinol-cyclodextrin complex in a heterotopic mouse model of glioma.","finding":"","journal":"European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V","studyType":"Clinical Study"},{"pmid":"21495268","year":"2010","title":"Speciation of arsenic in urine following intravenous administration of arsthinol in mice.","finding":"","journal":"European journal of drug metabolism and pharmacokinetics","studyType":"Clinical Study"},{"pmid":"19814860","year":"2009","title":"Arsthinol nanosuspensions: pharmacokinetics and anti-leukaemic activity on NB4 promyelocytic leukaemia cells.","finding":"","journal":"The Journal of pharmacy and pharmacology","studyType":"Clinical Study"},{"pmid":"17489071","year":"2007","title":"[Organoarsenicals derived from 2-phenyl-[1,3,2]dithiarsolan-4-yl)-methanol (AsIII) with antileukaemic properties: from trypanosomicides to anticancer drugs].","finding":"","journal":"Annales pharmaceutiques francaises","studyType":"Clinical Study"},{"pmid":"5708352","year":"1968","title":"Ultraviolet spectrum correlations with the conjugate acid-base species of acetarsone and arsthinol.","finding":"","journal":"Journal of pharmaceutical sciences","studyType":"Clinical Study"}],"tags":[{"label":"arsthinol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"P01AR01","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"balarsen","offLabel":[],"synonyms":["arsthinol","arsthinenol","mercaptoarsenol","balarsen"],"timeline":[],"brandName":"Balarsen","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"arsthinol","explanation":"Imagine your body's cells are like a orchestra, and each cell plays a specific note to create a symphony. ARSTHINOL is like a conductor that helps the cells play their notes in harmony, leading to a therapeutic effect. However, the exact way it conducts the cells is still unknown.","oneSentence":"ARSTHINOL works by interacting with a specific biological pathway to produce its therapeutic effect.","technicalDetail":"ARSTHINOL's mechanism of action is believed to involve the modulation of a specific biological pathway, although the exact target and molecular interactions are currently unknown."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3007","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ARSTHINOL","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:45:41.500779","biosimilars":[],"competitors":[],"genericName":"arsthinol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"QNT09A162Y","CHEBI":"CHEBI:135465","INN_ID":"240","UMLSCUI":"C0301341","ChEMBL_ID":"CHEMBL1788384","KEGG_DRUG":"D07356","DRUGBANK_ID":"DB08928","PUBCHEM_CID":"8414","SNOMEDCT_US":"14507006","MESH_SUPPLEMENTAL_RECORD_UI":"C546471"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":13,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"P01AR01","allCodes":["P01AR01"]},"biosimilarFilings":[],"recentPublications":[{"date":"2013 Nov","pmid":"23831266","title":"The antitumor effects of an arsthinol-cyclodextrin complex in a heterotopic mouse model of glioma.","journal":"European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V"},{"date":"2010 Sep","pmid":"21495268","title":"Speciation of arsenic in urine following intravenous administration of arsthinol in mice.","journal":"European journal of drug metabolism and pharmacokinetics"},{"date":"2009 Oct","pmid":"19814860","title":"Arsthinol nanosuspensions: pharmacokinetics and anti-leukaemic activity on NB4 promyelocytic leukaemia cells.","journal":"The Journal of pharmacy and pharmacology"},{"date":"2007 May","pmid":"17489071","title":"[Organoarsenicals derived from 2-phenyl-[1,3,2]dithiarsolan-4-yl)-methanol (AsIII) with antileukaemic properties: from trypanosomicides to anticancer drugs].","journal":"Annales pharmaceutiques francaises"},{"date":"1968 Dec","pmid":"5708352","title":"Ultraviolet spectrum correlations with the conjugate acid-base species of acetarsone and arsthinol.","journal":"Journal of pharmaceutical sciences"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"ARSTHINOL, also known as Balarsen, is a small molecule drug in the arsthinol class. Its exact target and mechanism of action are unknown, but it is believed to work by modulating a specific biological pathway. ARSTHINOL is not FDA-approved for any indications, and its commercial status, including patent and generic availability, is unclear. Further research is needed to determine its safety and efficacy. As a result, key safety considerations and approved indications are currently unavailable.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}