{"id":"arm-t1-primatene-mist-hfa","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Tremors"},{"rate":"5-10%","effect":"Nervousness"},{"rate":"5-10%","effect":"Palpitations"},{"rate":"5-10%","effect":"Headache"},{"rate":"5-10%","effect":"Dizziness"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Epinephrine is a sympathomimetic agent that stimulates the beta-2 adrenergic receptors in the lungs, causing bronchodilation. This helps to relieve bronchospasm and improve breathing in patients with asthma or chronic obstructive pulmonary disease (COPD).","oneSentence":"Primatene Mist HFA is a bronchodilator that contains epinephrine, which works by relaxing the muscles in the airways and increasing air flow to the lungs.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T02:29:17.408Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Relief of acute asthma symptoms"},{"name":"Relief of acute bronchospasm in COPD"}]},"trialDetails":[{"nctId":"NCT01143051","phase":"PHASE1, PHASE2","title":"Pharmacokinetics (PK) Study of Epinephrine Inhalation Aerosol in Healthy Volunteers","status":"COMPLETED","sponsor":"Amphastar Pharmaceuticals, Inc.","startDate":"2010-01","conditions":"Asthma","enrollment":24},{"nctId":"NCT01025648","phase":"PHASE1, PHASE2","title":"Randomized, Placebo/Active Crossover Dose-ranging Study for Safety and Efficacy in Asthma Patients.","status":"TERMINATED","sponsor":"Amphastar Pharmaceuticals, Inc.","startDate":"2009-12","conditions":"Asthma","enrollment":9},{"nctId":"NCT01255709","phase":"PHASE2","title":"Epinephrine Inhalation Aerosol USP, CLINICAL STUDY-B3 FOR ASSESSMENT OF PHARMACOKINETICS","status":"COMPLETED","sponsor":"Amphastar Pharmaceuticals, Inc.","startDate":"2010-12","conditions":"Asthma","enrollment":24}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["epinephrine inhalation aerosol"],"phase":"phase_2","status":"active","brandName":"Arm T1: Primatene Mist HFA","genericName":"Arm T1: Primatene Mist HFA","companyName":"Amphastar Pharmaceuticals, Inc.","companyId":"amphastar-pharmaceuticals-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Primatene Mist HFA is a bronchodilator that contains epinephrine, which works by relaxing the muscles in the airways and increasing air flow to the lungs. Used for Relief of acute asthma symptoms, Relief of acute bronchospasm in COPD.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}