{"id":"arificial-tear","safety":{"commonSideEffects":[{"rate":null,"effect":"Transient blurred vision"},{"rate":null,"effect":"Eye irritation"},{"rate":null,"effect":"Allergic reaction (rare)"}]},"_chembl":{"chemblId":"CHEMBL1457","moleculeType":"Small molecule","molecularWeight":"299.37"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Artificial tears mimic the composition and function of natural tears, providing lubrication to the ocular surface and protecting the cornea and conjunctiva from desiccation. They help restore the tear film's protective barrier, reduce friction during blinking, and provide comfort by moisturizing dry eye tissues. These formulations typically contain water, electrolytes, and viscosity agents to maintain prolonged contact with the eye surface.","oneSentence":"Artificial tears are lubricating eye drops that supplement or replace the eye's natural tear film to relieve dryness and irritation.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:18:00.153Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry eye syndrome"},{"name":"Ocular surface irritation and discomfort"}]},"trialDetails":[{"nctId":"NCT00553735","phase":"PHASE4","title":"The Prophylactic Use of Topical Cyclosporine A 0.05% to Prevent Graft Versus Host Disease Related Dry Eye","status":"TERMINATED","sponsor":"Massachusetts Eye and Ear Infirmary","startDate":"2007-08","conditions":"Dry Eye","enrollment":8}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Placebo","Artificial Tear"],"phase":"marketed","status":"active","brandName":"Arificial Tear","genericName":"Arificial Tear","companyName":"Massachusetts Eye and Ear Infirmary","companyId":"massachusetts-eye-and-ear-infirmary","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Artificial tears are lubricating eye drops that supplement or replace the eye's natural tear film to relieve dryness and irritation. Used for Dry eye syndrome, Ocular surface irritation and discomfort.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}