{"id":"ara-c","safety":{"commonSideEffects":[{"rate":"70-90","effect":"Myelosuppression (neutropenia, thrombocytopenia, anemia)"},{"rate":"50-70","effect":"Nausea and vomiting"},{"rate":"40-60","effect":"Mucositis"},{"rate":"30-50","effect":"Diarrhea"},{"rate":"10-25","effect":"Cerebellar syndrome (high-dose)"},{"rate":"5-15","effect":"Hepatotoxicity"},{"rate":"20-30","effect":"Alopecia"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Ara-C (cytarabine) is a nucleoside analog that mimics cytidine and becomes incorporated into DNA during the S phase of the cell cycle. Once integrated, it inhibits DNA polymerase and prevents further DNA synthesis, leading to cell death. 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