{"id":"application-of-carnoy-solution","safety":{"commonSideEffects":[{"rate":null,"effect":"Tissue irritation and chemical burn"},{"rate":null,"effect":"Mucosal damage"},{"rate":null,"effect":"Postoperative pain"}]},"_chembl":{"chemblId":"CHEMBL2108251","moleculeType":"Oligosaccharide"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Carnoy solution is a chemical fixative composed of ethanol, chloroform, and acetic acid that rapidly penetrates and fixes tissue by denaturing proteins and removing lipids. It is primarily used in surgical oncology and otolaryngology to chemically cauterize and harden tissue margins, particularly in endoscopic sinus surgery and tumor bed treatment. The solution acts as both a fixative for histopathological examination and a tissue-hardening agent to reduce bleeding and improve surgical visualization.","oneSentence":"Carnoy solution is a fixative and tissue-hardening agent used in surgical and pathological applications to preserve and harden tissue specimens.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:27:30.117Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Tissue fixation and hardening in endoscopic sinus surgery"},{"name":"Tumor bed treatment and margin control in surgical oncology"},{"name":"Hemostasis and tissue preservation in otolaryngological procedures"}]},"trialDetails":[{"nctId":"NCT06096220","phase":"PHASE4","title":"Usage of 5-fluorouracil and Carnoy's Solution in Surgical Treatment of Odontogenic Keratocysts","status":"ENROLLING_BY_INVITATION","sponsor":"University of Belgrade","startDate":"2023-06-10","conditions":"Odontogenic Keratocyst","enrollment":50}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":4,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Application of Carnoy solution","genericName":"Application of Carnoy solution","companyName":"University of Belgrade","companyId":"university-of-belgrade","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Carnoy solution is a fixative and tissue-hardening agent used in surgical and pathological applications to preserve and harden tissue specimens. Used for Tissue fixation and hardening in endoscopic sinus surgery, Tumor bed treatment and margin control in surgical oncology, Hemostasis and tissue preservation in otolaryngological procedures.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}