{"id":"apotel-max","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Hepatotoxicity (at high doses)"},{"rate":null,"effect":"Allergic reactions"}]},"_chembl":{"chemblId":"CHEMBL5095188","moleculeType":"Small molecule","molecularWeight":"527.54"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"APOTEL max typically combines paracetamol with another active ingredient (likely a non-steroidal anti-inflammatory drug or additional analgesic) to provide enhanced pain relief and fever reduction. Paracetamol acts as a cyclooxygenase inhibitor in the central nervous system, while co-formulated agents may provide peripheral anti-inflammatory effects, resulting in synergistic analgesic and antipyretic activity.","oneSentence":"APOTEL max is a fixed-dose combination of paracetamol (acetaminophen) and an additional analgesic or anti-inflammatory agent that works to reduce pain and fever through multiple pathways.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:17:34.027Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Mild to moderate pain"},{"name":"Fever reduction"}]},"trialDetails":[{"nctId":"NCT02283203","phase":"PHASE4","title":"A New Formulation of Intravenous Paracetamol for Fever Management","status":"COMPLETED","sponsor":"Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.","startDate":"2015-02","conditions":"Fever","enrollment":80}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Paracetamol solution for infusion, 1gram per 100ml bag"],"phase":"marketed","status":"active","brandName":"APOTEL max","genericName":"APOTEL max","companyName":"Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.","companyId":"uni-pharma-kleon-tsetis-pharmaceutical-laboratories-s-a","modality":"Small molecule","firstApprovalDate":"","aiSummary":"APOTEL max is a fixed-dose combination of paracetamol (acetaminophen) and an additional analgesic or anti-inflammatory agent that works to reduce pain and fever through multiple pathways. Used for Mild to moderate pain, Fever reduction.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}