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Severe liver damage may occur if you take: more than 4,000 mg in 24 hours, which is the maximum daily amount with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away."],"effective_time":"20240102","active_ingredient":["ACTIVE INGREDIENT Active ingredient (in each tablet) Acetaminophen 500 mg"],"inactive_ingredient":["Inactive ingredients corn starch, hypromellose*, polyethylene glycol*, povidone, pregelatinized corn starch*, sodium starch glycolate*, stearic acid*, titanium dioxide* *may contain"],"indications_and_usage":["Uses temporarily relieves minor aches and pains due to: headache muscular aches minor pain of arthritis backahe the common cold toothache premenstrual and menstrual cramps temporarily reduces fever"],"other_safety_information":["Other information store at room temperature 59º-86ºF (15º-30ºC) tamper-evident sealed packets do not use any opened or torn packets"],"spl_unclassified_section":["Drug Facts","DO NOT USE Do not use with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are allergic to acetaminophen or any of the inactive ingredients in this product","ASK DOCTOR Ask a doctor before use if you have liver disease","ASK DOCTOR/PHARMACIST Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin","STOP USE Stop use and ask a doctor if pain gets worse or lasts for more than 10 days fever gets worse or lasts for more than 3 days new symptoms occur redness or swelling is present These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.","QUESTIONS Questions or comments? 1-800-634-7680"],"dosage_and_administration":["Directions do not use more than directed (see overdose warning) ​ Adults and children: (12 years and over) take 2 tablets every 6 hours while symptoms last. do not take more than 6 tablets in 24 hours, unless directed by a doctor do not use for more than 10 days unless directed by a doctor Children under 12 years: Ask a doctor"],"spl_product_data_elements":["MEDIQUE APAP EXTRA STRENGTH acetaminophen tablet, film coated MEDIQUE APAP EXTRA STRENGTH acetaminophen tablet, film coated POVIDONE SODIUM STARCH GLYCOLATE TYPE A POTATO HYPROMELLOSES STARCH, CORN ACETAMINOPHEN ACETAMINOPHEN STEARIC ACID TITANIUM DIOXIDE POLYETHYLENE GLYCOL, UNSPECIFIED AZ;235"],"keep_out_of_reach_of_children":["KEEP OUT OF REACH OF CHILDREN KEEP OUT OF REACH OF CHILDREN"],"package_label_principal_display_panel":["SERIALIZED LABEL"]},"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Oral","category":"route"},{"label":"Active","category":"status"},{"label":"headache","category":"indication"},{"label":"muscular aches","category":"indication"},{"label":"minor pain of arthritis","category":"indication"},{"label":"backache","category":"indication"},{"label":"the common cold","category":"indication"},{"label":"toothache","category":"indication"},{"label":"HF Acquisition Co LLC, DBA HealthFirst","category":"company"}],"phase":"marketed","safety":{"boxedWarnings":[]},"trials":[],"aliases":[],"company":"HF Acquisition Co LLC, DBA HealthFirst","patents":[],"pricing":[],"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=APAP","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T00:24:01.164045+00:00"},"aiSummary":{"url":"","method":"ai_extraction","source":"AI Strategic Summary","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"ai_extraction","retrievedAt":"2026-04-20T00:24:48.108888+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T00:24:11.955513+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=APAP","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T00:24:12.755074+00:00"},"administration.route":{"url":"","method":"deterministic","source":"FDA Label","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T00:23:58.921399+00:00"},"indications.approved":{"url":"","method":"ai_extraction","source":"FDA Label + AI","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"fda_label","retrievedAt":"2026-04-20T00:24:42.654113+00:00"},"safety.boxedWarnings":{"url":"","method":"deterministic","source":"FDA Label (no boxed warning)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T00:23:58.921526+00:00"},"crossReferences.chemblId":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL1795485/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-20T00:24:13.230114+00:00"},"regulatory.fda_application":{"url":"","method":"deterministic","source":"FDA Label","rawText":"505G(a)(3)","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T00:23:58.921537+00:00"}},"allNames":"medique apap extra strength acetaminophen tablet, film coated","offLabel":[],"synonyms":["MEDIQUE APAP EXTRA STRENGTH acetaminophen tablet, film coated","ACETAMINOPHEN"],"timeline":[],"aiSummary":"APAP, marketed by HF Acquisition Co LLC, DBA HealthFirst, is an extra-strength acetaminophen tablet used primarily for headache relief. 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