{"id":"any-fda-approved-alk-inhibitors","safety":{"commonSideEffects":[{"rate":"34%","effect":"Diarrhea"},{"rate":"31%","effect":"Nausea"},{"rate":"21%","effect":"Vomiting"},{"rate":"19%","effect":"Fatigue"},{"rate":"17%","effect":"Weight loss"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Inhibits the activity of the anaplastic lymphoma kinase (ALK) protein, which is involved in the development and progression of certain cancers.","oneSentence":"ALK tyrosine kinase inhibitor","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:56:55.738Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Non-small cell lung cancer"}]},"trialDetails":[{"nctId":"NCT03546894","phase":"","title":"A Study to Determine Progression-free Survival (PFS) and Evaluate Participant Experience for Participants With Metastatic Anaplastic Lymphoma Kinase-positive (ALK+) Non-Small Cell Lung Cancer (NSCLC) Treated With Anaplastic Lymphoma Kinase (ALK) Inhibitors","status":"COMPLETED","sponsor":"Takeda","startDate":"2018-07-23","conditions":"Anaplastic Lymphoma Kinase-positive, Carcinoma Non-small-cell Lung","enrollment":111}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":9,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Any FDA Approved ALK Inhibitors","genericName":"Any FDA Approved ALK Inhibitors","companyName":"Takeda","companyId":"takeda","modality":"Small molecule","firstApprovalDate":"","aiSummary":"ALK tyrosine kinase inhibitor Used for Non-small cell lung cancer.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}