{"id":"antiseptic-cleanser","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation or erythema"},{"rate":null,"effect":"Allergic contact dermatitis"},{"rate":null,"effect":"Drying of skin"}]},"_chembl":null,"_dailymed":{"setId":"46dc074c-af71-4805-e054-00144ff8d46c","title":"ANTISEPTIC SKIN CLEANSER (CHLORHEXIDINE GLUCONATE 4%) LIQUID [CVS PHARMACY, INC.]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Antiseptic cleansers work by disrupting bacterial cell membranes, denaturing proteins, or interfering with microbial metabolism, thereby reducing the microbial load on skin and tissues. These products are typically used for preoperative skin preparation, wound cleaning, and general antisepsis in clinical and surgical settings. The specific mechanism depends on the active ingredient (e.g., chlorhexidine, iodine, alcohol, or other antimicrobial agents).","oneSentence":"An antiseptic cleanser reduces or eliminates microorganisms on skin and wound surfaces through chemical antimicrobial action.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:17:31.107Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Preoperative skin antisepsis"},{"name":"Wound cleaning and antisepsis"},{"name":"General skin antisepsis in orthopedic procedures"}]},"trialDetails":[{"nctId":"NCT06712433","phase":"PHASE2","title":"Bacterial Decolonization Plus Intraoperative Angiography for Soft Tissue Sarcomas Receiving Preoperative Radiotherapy (CONCERTO)","status":"NOT_YET_RECRUITING","sponsor":"Adam Olson","startDate":"2026-09-30","conditions":"Sarcoma,Soft Tissue","enrollment":31},{"nctId":"NCT07142408","phase":"PHASE3","title":"The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal","status":"RECRUITING","sponsor":"The Cooper Health System","startDate":"2023-03-13","conditions":"Surgical Wound Infection","enrollment":848},{"nctId":"NCT06616844","phase":"NA","title":"IDEAL: Efficacy of Porcine Placental Extracellular Matrix Augmented Plus Standard of Care (SOC) Versus SOC Alone for the Management of Diabetic Foot Ulcers","status":"RECRUITING","sponsor":"ConvaTec Inc.","startDate":"2025-02-12","conditions":"Wound Heal, Ulcer","enrollment":194},{"nctId":"NCT05401292","phase":"PHASE4","title":"Skin Preparation for Elective Foot and Ankle Surgery","status":"RECRUITING","sponsor":"University of Missouri-Columbia","startDate":"2022-02-15","conditions":"Microbial Colonization, Foot and Ankle Disorders","enrollment":100},{"nctId":"NCT04450693","phase":"PHASE3","title":"Cryopreserved Human Umbilical Cord (TTAX01) for Late Stage, Complex Non-healing Diabetic Foot Ulcers (AMBULATE DFU II)","status":"COMPLETED","sponsor":"BioTissue Holdings, Inc","startDate":"2020-11-20","conditions":"Diabetic Foot Infection, Non-healing Wound, Non-healing Diabetic Foot Ulcer","enrollment":106},{"nctId":"NCT03938467","phase":"PHASE4","title":"Irrisept C.Acnes Study","status":"COMPLETED","sponsor":"Orthopaedic Associates of Michigan, PC","startDate":"2021-03-01","conditions":"Rate of Positive Culture Growth for C.Acnes From Specimens Obtained From the Shoulders of Patients Undergoing Primary Shoulder Arthroplasty","enrollment":58},{"nctId":"NCT04176120","phase":"PHASE3","title":"Cryopreserved Human Umbilical Cord (TTAX01) for Late Stage, Complex Non-healing Diabetic Foot Ulcers (AMBULATE DFU)","status":"COMPLETED","sponsor":"BioTissue Holdings, Inc","startDate":"2020-07-01","conditions":"Diabetic Foot Infection, Non-healing Wound, Non-healing Diabetic Foot Ulcer","enrollment":220},{"nctId":"NCT05196191","phase":"NA","title":"Wound Healing Following Penile Prosthesis Implant","status":"TERMINATED","sponsor":"VIVEX Biologics, Inc.","startDate":"2022-01-03","conditions":"Erectile Dysfunction","enrollment":32},{"nctId":"NCT04723446","phase":"NA","title":"Efficacy of Mouthwashes in Reducing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Viral Load in the Saliva","status":"COMPLETED","sponsor":"Queen Mary University of London","startDate":"2021-05-19","conditions":"Covid19, Coronavirus","enrollment":54},{"nctId":"NCT04218799","phase":"PHASE4","title":"Human Microbiome and Healthcare Associated Infections - Nursing Home Dwelling Older Veterans","status":"COMPLETED","sponsor":"University of Maryland, Baltimore","startDate":"2014-08-12","conditions":"Human Microbiome","enrollment":19},{"nctId":"NCT04320628","phase":"NA","title":"Randomized Double-Blind Controlled Clinical Trial","status":"COMPLETED","sponsor":"SerenaGroup, Inc.","startDate":"2020-05-20","conditions":"Chronic Wounds, Acute Wounds","enrollment":25},{"nctId":"NCT04222699","phase":"PHASE4","title":"Cultures Before and After Decolonization in Community Dwelling Adults With Current S. Aureus Colonization","status":"COMPLETED","sponsor":"VA Office of Research and Development","startDate":"2012-09-18","conditions":"Human Microbiome","enrollment":58},{"nctId":"NCT01657318","phase":"","title":"Olivamine-containing Products in the Management of Patients With Nonhealing Lower Extremity Ulcers","status":"TERMINATED","sponsor":"De La Salle University Medical Center","startDate":"2012-09-01","conditions":"Ulcer, Skin Ulcer, Leg Ulcer","enrollment":5},{"nctId":"NCT03348917","phase":"PHASE4","title":"The Effect of Skin Cleansers on the Skin Surface Microbiome","status":"COMPLETED","sponsor":"Mundipharma Manufacturing Pte Ltd.","startDate":"2017-12-28","conditions":"Skin Health","enrollment":15},{"nctId":"NCT01717690","phase":"PHASE4","title":"Study of 2% Chlorhexidine Gluconate-Impregnated Bath Cloths to Prevent MRSA Colonization in Complex Continuing Care","status":"COMPLETED","sponsor":"Baycrest","startDate":"2013-08","conditions":"Staph Aureus Methicillin Resistant Colonization","enrollment":122}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":133,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Irrisept Wound Cleansing System"],"phase":"marketed","status":"active","brandName":"Antiseptic Cleanser","genericName":"Antiseptic Cleanser","companyName":"Orthopaedic Associates of Michigan, PC","companyId":"orthopaedic-associates-of-michigan-pc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"An antiseptic cleanser reduces or eliminates microorganisms on skin and wound surfaces through chemical antimicrobial action. Used for Preoperative skin antisepsis, Wound cleaning and antisepsis, General skin antisepsis in orthopedic procedures.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}