{"id":"antipyrine-benzocaine-otic-solution","safety":{"commonSideEffects":[{"rate":"null","effect":"Ear discomfort"},{"rate":"null","effect":"Hearing loss"}]},"_chembl":{"chemblId":"CHEMBL278172","moleculeType":"Small molecule","molecularWeight":"165.19"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"The combination of antipyrine and benzocaine in this otic solution helps to reduce pain and inflammation in the ear, while also providing a numbing effect to make procedures less uncomfortable.","oneSentence":"Antipyrine-benzocaine otic solution works by providing local anesthetic and analgesic effects to the ear.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T04:10:50.122Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Ear pain relief"},{"name":"Otitis externa treatment"}]},"trialDetails":[{"nctId":"NCT02037893","phase":"PHASE2","title":"Four Arm Safety & Efficacy With Antipyrine and Benzocaine Otic Solution in Children With Acute Otitis Media","status":"COMPLETED","sponsor":"Currax Pharmaceuticals","startDate":"2013-11","conditions":"Acute Otitis Media","enrollment":112},{"nctId":"NCT02153541","phase":"PHASE2","title":"Assessing the Efficacy of CREWS01 to Decrease Usage of Rescue Inhalers in Moderate to Severe Asthmatic Adults","status":"UNKNOWN","sponsor":"Global United Pharmaceutical Corporation","startDate":"2023-04-01","conditions":"Asthma","enrollment":50}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Antipyrine-benzocaine otic solution","genericName":"Antipyrine-benzocaine otic solution","companyName":"Global United Pharmaceutical Corporation","companyId":"global-united-pharmaceutical-corporation","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Antipyrine-benzocaine otic solution works by providing local anesthetic and analgesic effects to the ear. Used for Ear pain relief, Otitis externa treatment.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}