{"id":"antiperspirant-cream-f511","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation or contact dermatitis"},{"rate":null,"effect":"Allergic reaction to active ingredients"},{"rate":null,"effect":"Local erythema or rash"}]},"_chembl":{"chemblId":"CHEMBL2108947","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"The drug functions as a topical antiperspirant, working to inhibit or reduce perspiration at the skin surface. The exact molecular mechanism is not publicly detailed, but antiperspirants typically work by forming a plug in sweat ducts or by reducing sweat secretion through aluminum compounds or alternative active ingredients. As a Phase 3 candidate from Swiss Cancer Institute, it may have been developed for specific clinical applications beyond cosmetic use.","oneSentence":"Antiperspirant cream F511 reduces sweat production by blocking eccrine sweat gland activity, likely through aluminum salt-based or similar astringent mechanisms.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:01:55.615Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hyperhidrosis or excessive sweating (presumed, based on antiperspirant classification)"}]},"trialDetails":[{"nctId":"NCT00992706","phase":"PHASE3","title":"F511 Cream in Preventing Palmar-Plantar Erythrodysesthesia in Patients Receiving Doxorubicin Hydrochloride Liposome for Metastatic Breast Cancer","status":"COMPLETED","sponsor":"Swiss Cancer Institute","startDate":"2009-09","conditions":"Breast Cancer, Palmar-plantar Erythrodysesthesia","enrollment":91}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"antiperspirant cream F511","genericName":"antiperspirant cream F511","companyName":"Swiss Cancer Institute","companyId":"swiss-cancer-institute","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Antiperspirant cream F511 reduces sweat production by blocking eccrine sweat gland activity, likely through aluminum salt-based or similar astringent mechanisms. Used for Hyperhidrosis or excessive sweating (presumed, based on antiperspirant classification).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}