{"id":"anti-csbd-bovine-igg","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"This bovine immunoglobulin G antibody is designed to neutralize or block the CsbD antigen, which may be expressed by pathogenic bacteria or involved in disease pathogenesis. By binding to CsbD, the antibody aims to prevent bacterial virulence mechanisms or enhance immune clearance. The use of bovine-derived antibodies provides a source of polyclonal or monoclonal immunoglobulins for passive immunization.","oneSentence":"Anti-CsbD bovine IgG is a passive immunotherapy that targets the CsbD protein, likely involved in bacterial pathogenesis or immune evasion.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T04:10:00.913Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Bacterial infection or disease associated with CsbD antigen expression (specific indication not publicly detailed)"}]},"trialDetails":[{"nctId":"NCT00524004","phase":"PHASE2","title":"Safety and Efficacy of Bovine Milk Immunoglobulin Against CS17 and CsbD","status":"COMPLETED","sponsor":"Johns Hopkins Bloomberg School of Public Health","startDate":"2007-01-30","conditions":"Travelers' Diarrhea","enrollment":36}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Experimental"],"phase":"phase_2","status":"active","brandName":"Anti-CsbD Bovine IgG","genericName":"Anti-CsbD Bovine IgG","companyName":"Johns Hopkins Bloomberg School of Public Health","companyId":"johns-hopkins-bloomberg-school-of-public-health","modality":"Biologic","firstApprovalDate":"","aiSummary":"Anti-CsbD bovine IgG is a passive immunotherapy that targets the CsbD protein, likely involved in bacterial pathogenesis or immune evasion. Used for Bacterial infection or disease associated with CsbD antigen expression (specific indication not publicly detailed).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}