{"id":"ankle-onq","safety":{"commonSideEffects":[{"rate":null,"effect":"Catheter-related complications (migration, kinking, dislodgement)"},{"rate":null,"effect":"Local anesthetic toxicity"},{"rate":null,"effect":"Infection at catheter site"},{"rate":null,"effect":"Nerve injury"}]},"_chembl":{"chemblId":"CHEMBL1457","moleculeType":"Small molecule","molecularWeight":"299.37"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The system consists of a small catheter placed near peripheral nerves in the ankle region, connected to a disposable elastomeric pump that continuously infuses local anesthetic (typically liposomal bupivacaine) over several days. This provides sustained regional anesthesia and analgesia without systemic opioid exposure, reducing pain and potentially improving recovery outcomes after ankle surgery.","oneSentence":"Ankle OnQ is a continuous peripheral nerve block catheter system that delivers local anesthetic directly to nerve tissue around the ankle to provide prolonged postoperative pain relief.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:16:51.997Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Postoperative pain management following ankle surgery"}]},"trialDetails":[{"nctId":"NCT02280291","phase":"PHASE4","title":"Single Shot Versus OnQ Pump in Extremity Fractures","status":"COMPLETED","sponsor":"NYU Langone Health","startDate":"2013-08","conditions":"Pain, Fracture","enrollment":100}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Ankle OnQ","genericName":"Ankle OnQ","companyName":"NYU Langone Health","companyId":"nyu-langone-health","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ankle OnQ is a continuous peripheral nerve block catheter system that delivers local anesthetic directly to nerve tissue around the ankle to provide prolonged postoperative pain relief. Used for Postoperative pain management following ankle surgery.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}