{"id":"aniracetam","rwe":[{"pmid":"41737153","year":"2026","title":"Efficacy of Huoxue Tongqiao Decoction combined with aniracetam in treating post-stroke cognitive impairment in elderly patients with ischemic stroke and its effects on serum levels of superoxide dismutase, glutathione peroxidase and nitric oxide.","finding":"","journal":"Pakistan journal of medical sciences","studyType":"Clinical Study"},{"pmid":"41644999","year":"2026","title":"Aniracetam restores the excitation-inhibition balance of neurotransmitters in the prefrontal cortex of mice with ADHD.","finding":"","journal":"Scientific reports","studyType":"Clinical Study"},{"pmid":"41265341","year":"2026","title":"A deep representation learning algorithm on drug-target interaction to screen novel drug candidates for Alzheimer's disease.","finding":"","journal":"Artificial intelligence in medicine","studyType":"Clinical Study"},{"pmid":"40525420","year":"2025","title":"Identification of Potential FDA-Approved Inhibitors of SARS-CoV-2 Helicase Through a Multistep In silico Approach: A Promising Prospect for COVID-19 Treatment.","finding":"","journal":"Medicinal chemistry (Shariqah (United Arab Emirates))","studyType":"Clinical Study"},{"pmid":"40118526","year":"2025","title":"Aniracetam Ameliorates Attention Deficit Hyperactivity Disorder Behavior in Adolescent Mice.","finding":"","journal":"eNeuro","studyType":"Clinical Study"}],"tags":[{"label":"aniracetam","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"N06BX11","category":"atc"},{"label":"Active","category":"status"},{"label":"Antidepressive Agents","category":"pharmacology"},{"label":"Central Nervous System Agents","category":"pharmacology"},{"label":"Nootropic Agents","category":"pharmacology"},{"label":"Psychotropic Drugs","category":"pharmacology"}],"phase":"phase_2","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"ampamet","offLabel":[],"synonyms":["aniracetam","ampamet","draganon","memodrin"],"timeline":[],"brandName":"Ampamet","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"aniracetam","explanation":"Think of it like a key that unlocks a door in your brain. Aniracetam helps turn up the volume on certain chemical signals that help us learn and remember new information. This can make it easier to focus and pay attention.","oneSentence":"Aniracetam works by enhancing the activity of glutamate receptors and increasing the release of the neurotransmitter acetylcholine.","technicalDetail":"Aniracetam acts as a potent agonist of the AMPA receptor subtype of glutamate receptors, increasing the frequency of excitatory postsynaptic potentials and enhancing synaptic plasticity."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/221","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ANIRACETAM","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:48:25.094294","biosimilars":[],"competitors":[],"genericName":"aniracetam","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"006974","UNII":"5L16LKN964","CHEBI":"CHEBI:47943","INN_ID":"4902","RXNORM":"17939","UMLSCUI":"C0051917","ChEMBL_ID":"CHEMBL36994","KEGG_DRUG":"D01883","DRUGBANK_ID":"DB04599","PDB_CHEM_ID":" 4MP","PUBCHEM_CID":"2196","IUPHAR_LIGAND_ID":"4133","MESH_SUPPLEMENTAL_RECORD_UI":"C036466"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":296,"therapeuticAreas":["Neuroscience"],"atcClassification":{"source":"DrugCentral","atcCode":"N06BX11","allCodes":["N06BX11"]},"biosimilarFilings":[],"recentPublications":[{"date":"2026 Jan","pmid":"41737153","title":"Efficacy of Huoxue Tongqiao Decoction combined with aniracetam in treating post-stroke cognitive impairment in elderly patients with ischemic stroke and its effects on serum levels of superoxide dismutase, glutathione peroxidase and nitric oxide.","journal":"Pakistan journal of medical sciences"},{"date":"2026 Feb 5","pmid":"41644999","title":"Aniracetam restores the excitation-inhibition balance of neurotransmitters in the prefrontal cortex of mice with ADHD.","journal":"Scientific reports"},{"date":"2026 Jan","pmid":"41265341","title":"A deep representation learning algorithm on drug-target interaction to screen novel drug candidates for Alzheimer's disease.","journal":"Artificial intelligence in medicine"},{"date":"2025","pmid":"40525420","title":"Identification of Potential FDA-Approved Inhibitors of SARS-CoV-2 Helicase Through a Multistep In silico Approach: A Promising Prospect for COVID-19 Treatment.","journal":"Medicinal chemistry (Shariqah (United Arab Emirates))"},{"date":"2025 Mar","pmid":"40118526","title":"Aniracetam Ameliorates Attention Deficit Hyperactivity Disorder Behavior in Adolescent Mice.","journal":"eNeuro"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ampamet, also known as Aniracetam, is a small molecule. It is a synthetic compound with the chemical name 1-P-ANISOYL-2-PYRROLIDINONE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}