{"id":"angongniuhuang-pill","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Allergic reactions"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This herbal compound combines ingredients traditionally believed to have antipyretic, sedative, and neuroprotective properties. It is used in Chinese medicine to address febrile conditions with delirium, seizures, or loss of consciousness by cooling internal heat and restoring mental clarity. The exact molecular mechanisms remain incompletely characterized by Western pharmacology standards.","oneSentence":"Angong Niuhuang pill is a traditional Chinese medicine formulation that clears heat, resolves toxicity, and opens the sensory orifices to treat high fever and altered consciousness.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:42:11.207Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"High fever with delirium or altered consciousness"},{"name":"Febrile seizures"},{"name":"Encephalitis or meningitis (adjunctive treatment)"}]},"trialDetails":[{"nctId":"NCT04475328","phase":"PHASE3","title":"Efficacy and Safety of AngongNiuhuang Pill in Patients With Acute Ischemic Stroke (ANGONG TRIAL)","status":"COMPLETED","sponsor":"Peking Union Medical College Hospital","startDate":"2020-10-01","conditions":"Acute Ischemic Stroke","enrollment":120},{"nctId":"NCT03733002","phase":"PHASE3","title":"Efficacy and Safety of AngongNiuhuang Pill for the Treatment of Patients With Acute Ischemic Stroke.","status":"UNKNOWN","sponsor":"Peking Union Medical College Hospital","startDate":"2018-12-01","conditions":"Acute Ischemic Stroke","enrollment":100},{"nctId":"NCT00817609","phase":"PHASE2, PHASE3","title":"Effectiveness and Safety of Angongniuhuang Pill on Restoring Consciousness for Patients Who Have Suffered From a Stroke","status":"UNKNOWN","sponsor":"Fudan University","startDate":"","conditions":"Stroke, Acute Ischemic Stroke","enrollment":60}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Angong Niuhuang Wan"],"phase":"phase_3","status":"active","brandName":"AngongNiuhuang pill","genericName":"AngongNiuhuang pill","companyName":"Peking Union Medical College Hospital","companyId":"peking-union-medical-college-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Angong Niuhuang pill is a traditional Chinese medicine formulation that clears heat, resolves toxicity, and opens the sensory orifices to treat high fever and altered consciousness. Used for High fever with delirium or altered consciousness, Febrile seizures, Encephalitis or meningitis (adjunctive treatment).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":2,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}