{"id":"anesthesics-plus-antiinflammatory-clife1","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This combination drug is designed to deliver both local or general anesthetic effects to block pain sensation while concurrently suppressing inflammatory pathways. By addressing both pain and inflammation together, the formulation aims to improve patient comfort and reduce tissue damage associated with inflammatory conditions. The exact molecular targets and specific anesthetic/anti-inflammatory agents in CLIFE1 are not publicly detailed.","oneSentence":"CLIFE1 combines anesthetic and anti-inflammatory properties to provide pain relief and reduce inflammatory responses simultaneously.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:16:55.887Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Perioperative pain and inflammation management"}]},"trialDetails":[{"nctId":"NCT02961855","phase":"PHASE4","title":"Efficacy and Safety of CLIFE1 Gel in Benign Anorectal Surgery","status":"COMPLETED","sponsor":"Hospital de Viladecans","startDate":"2011-01","conditions":"Fissure;Anal, Fistula;Rectal, Hemorrhoids","enrollment":120}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["lidocaine plus diclofenac","CLIFE1 topical gel"],"phase":"marketed","status":"active","brandName":"anesthesics plus antiinflammatory, CLIFE1","genericName":"anesthesics plus antiinflammatory, CLIFE1","companyName":"Hospital de Viladecans","companyId":"hospital-de-viladecans","modality":"Small molecule","firstApprovalDate":"","aiSummary":"CLIFE1 combines anesthetic and anti-inflammatory properties to provide pain relief and reduce inflammatory responses simultaneously. Used for Perioperative pain and inflammation management.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}