{"id":"andriol-testocaps","safety":{"commonSideEffects":[{"rate":null,"effect":"Polycythemia"},{"rate":null,"effect":"Acne"},{"rate":null,"effect":"Gynecomastia"},{"rate":null,"effect":"Mood changes"},{"rate":null,"effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Testosterone undecanoate is a long-chain ester of testosterone that is absorbed via the lymphatic system when taken orally with food, bypassing first-pass hepatic metabolism. This allows oral delivery of testosterone while maintaining physiological levels. The testosterone then binds to androgen receptors throughout the body to restore secondary sexual characteristics and metabolic function in testosterone-deficient men.","oneSentence":"Andriol Testocaps delivers testosterone undecanoate in lipid-based capsules to replace deficient testosterone in hypogonadal men.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:27:16.926Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Testosterone replacement therapy in adult males with hypogonadism"}]},"trialDetails":[{"nctId":"NCT00239590","phase":"PHASE2","title":"Testosterone and Myocardial Perfusion in Coronary Heart Disease (CHD)","status":"COMPLETED","sponsor":"Imperial College London","startDate":"2001-06","conditions":"Coronary Heart Disease","enrollment":28},{"nctId":"NCT01510847","phase":"PHASE4","title":"The Effect of 90-day Oral Testosterone Therapy in Chinese Males With Type 2 Diabetes (T2DM)","status":"TERMINATED","sponsor":"Singapore Clinical Research Institute","startDate":"2011-10","conditions":"Assess the Effects of a the 90-day Oral TS Study Regimen on PSA, IPSS, Haemoglobin and Haematocrit, and to Assess Adverse and Serious Adverse Events.","enrollment":19},{"nctId":"NCT00434824","phase":"PHASE2","title":"Effects of Andriol Testocaps in Symptomatic Late-Onset Hypogonadism (43203)","status":"COMPLETED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2001-11","conditions":"Hypogonadism, Androgens","enrollment":322}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":11,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Andriol Testocaps","genericName":"Andriol Testocaps","companyName":"Singapore Clinical Research Institute","companyId":"singapore-clinical-research-institute","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Andriol Testocaps delivers testosterone undecanoate in lipid-based capsules to replace deficient testosterone in hypogonadal men. Used for Testosterone replacement therapy in adult males with hypogonadism.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}