{"id":"an2898-ointment-1","safety":{"commonSideEffects":[{"rate":"null","effect":"Skin atrophy"}]},"_chembl":{"chemblId":"CHEMBL2108523","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"AN2898 ointment works by inhibiting the production of inflammatory mediators, such as prostaglandins and leukotrienes, which contribute to the symptoms of inflammation and itching. This is achieved through the suppression of the immune system's response, specifically the activation of T-lymphocytes and the release of cytokines. As a result, AN2898 ointment provides relief from the symptoms of inflammation and itching associated with various skin conditions.","oneSentence":"AN2898 ointment is a topical corticosteroid that reduces inflammation and itching by suppressing the immune system's response.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T04:09:09.075Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of mild to moderate atopic dermatitis"}]},"trialDetails":[{"nctId":"NCT01301508","phase":"PHASE2","title":"Efficacy and Safety of AN2898 and AN2728 Topical Ointments to Treat Mild-to-Moderate Atopic Dermatitis","status":"COMPLETED","sponsor":"Pfizer","startDate":"2011-05","conditions":"Dermatitis, Atopic","enrollment":46}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"AN2898 ointment, 1%","genericName":"AN2898 ointment, 1%","companyName":"Pfizer","companyId":"pfizer","modality":"Small molecule","firstApprovalDate":"","aiSummary":"AN2898 ointment is a topical corticosteroid that reduces inflammation and itching by suppressing the immune system's response. Used for Treatment of mild to moderate atopic dermatitis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}