{"id":"an2728-topical-ointment-2-qd","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Application site reactions"},{"rate":"5-10%","effect":"Headache"},{"rate":"5-10%","effect":"Nausea"}]},"_chembl":{"chemblId":"CHEMBL2108523","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"AN2728 works by modulating the immune response in the skin, reducing inflammation and potentially treating conditions such as psoriasis. The exact mechanism is not fully understood, but it is thought to involve the inhibition of certain immune cells in the skin.","oneSentence":"AN2728 Topical Ointment, 2% QD is a topical ointment that targets the skin's immune response.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T04:09:05.576Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Moderate to severe plaque psoriasis"}]},"trialDetails":[{"nctId":"NCT01602341","phase":"PHASE2","title":"Efficacy and Safety of AN2728 Topical Ointment to Treat Adolescents With Atopic Dermatitis","status":"COMPLETED","sponsor":"Pfizer","startDate":"2012-08","conditions":"Dermatitis, Atopic","enrollment":86}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"AN2728 Topical Ointment, 2% QD","genericName":"AN2728 Topical Ointment, 2% QD","companyName":"Pfizer","companyId":"pfizer","modality":"Small molecule","firstApprovalDate":"","aiSummary":"AN2728 Topical Ointment, 2% QD is a topical ointment that targets the skin's immune response. Used for Moderate to severe plaque psoriasis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}