{"id":"amtolmetin-guacil","rwe":[],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Analgesics","category":"pharmacology"},{"label":"Analgesics, Non-Narcotic","category":"pharmacology"},{"label":"Anti-Inflammatory Agents","category":"pharmacology"},{"label":"Anti-Inflammatory Agents, Non-Steroidal","category":"pharmacology"},{"label":"Antirheumatic Agents","category":"pharmacology"},{"label":"Peripheral Nervous System Agents","category":"pharmacology"},{"label":"Sensory System Agents","category":"pharmacology"}],"phase":"phase_2","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"artromed","offLabel":[],"synonyms":["amtolmetineguacil","ST-679","amtolmetin guacil","amtolmetin guacyl","artromed"],"timeline":[],"brandName":"Artromed","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells are like a orchestra, and each cell plays a specific role. Artromed is like a conductor that helps the cells work together in harmony to produce the right response. By interacting with specific biological pathways, Artromed can help to reduce inflammation and pain, but the exact details of how it does this are still not fully understood.","oneSentence":"Artromed works by interacting with specific biological pathways to produce its therapeutic effects.","technicalDetail":"Artromed is a small molecule that likely works by binding to specific receptors or enzymes, triggering a cascade of downstream effects that ultimately lead to its therapeutic effects. The exact molecular mechanisms involved are not publicly disclosed, but it is likely to involve modulation of inflammatory pathways and/or pain signaling pathways."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/204","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=AMTOLMETIN%20GUACIL","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=AMTOLMETIN GUACIL","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:47:33.382431","biosimilars":[],"competitors":[],"genericName":"amtolmetin guacil","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[{"nctId":"NCT02865161","phase":"","title":"Amtolmetin Gaucil in Knee Osteoarthritis","status":"COMPLETED","sponsor":"Dr. Reddy's Laboratories Limited","startDate":"2015-02","conditions":["Knee Osteoarthritis"],"enrollment":220,"completionDate":"2015-12"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"323A00CRO9","CHEBI":"CHEBI:135678","INN_ID":"6772","UMLSCUI":"C2346755","ChEMBL_ID":"CHEMBL1766570","KEGG_DRUG":"D07453","DRUGBANK_ID":"DB16088","PUBCHEM_CID":"65655","SECONDARY_CAS_RN":"87344-05-6","MESH_SUPPLEMENTAL_RECORD_UI":"C065762"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":7,"therapeuticAreas":["Pain"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Artromed is a small molecule with the synonyms including Artromed. It is being studied in clinical trials for conditions such as Neurofibromatosis Type 1 and Muscle Weakness, with interventions including whole-body vibration and muscle strengthening exercises.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}