{"id":"amosulalol","rwe":[],"tags":[{"label":"amosulalol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Adrenergic Agents","category":"pharmacology"},{"label":"Adrenergic Antagonists","category":"pharmacology"},{"label":"Adrenergic alpha-Antagonists","category":"pharmacology"},{"label":"Adrenergic beta-Antagonists","category":"pharmacology"},{"label":"Antihypertensive Agents","category":"pharmacology"},{"label":"Cardiovascular Agents","category":"pharmacology"},{"label":"Neurotransmitter Agents","category":"pharmacology"}],"phase":"phase_2","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["amosulalol hydrochloride","amosulalol","amosulalol HCl"],"offLabel":[],"synonyms":["amosulalol hydrochloride","amosulalol","amosulalol HCl"],"timeline":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"amosulalol","explanation":"Think of it like a brake pedal in a car - amosulalol helps slow down the heart rate and reduce blood pressure by blocking the enzymes that normally speed it up. This can help people with certain heart conditions or high blood pressure. By reducing the workload on the heart, amosulalol can help prevent complications and improve overall cardiovascular health.","oneSentence":"Amosulalol works by blocking the action of certain enzymes that regulate heart rate and blood pressure.","technicalDetail":"Amosulalol is a non-selective beta-1 and beta-2 adrenergic receptor blocker, which means it inhibits the activity of both types of beta receptors in the heart and other tissues, leading to decreased heart rate and contractility, and vasodilation."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/190","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=AMOSULALOL","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:43:05.675131","biosimilars":[],"competitors":[],"genericName":"amosulalol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"010910","UNII":"C69JI1BAU8","CHEBI":"CHEBI:31208","INN_ID":"5409","UMLSCUI":"C0103116","ChEMBL_ID":"CHEMBL152231","KEGG_DRUG":"D01469","PUBCHEM_CID":"2169","SECONDARY_CAS_RN":"70958-86-0","MESH_SUPPLEMENTAL_RECORD_UI":"C032473"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"pharmacokinetics":{"source":"DrugCentral","bioavailability":"99%"},"publicationCount":33,"therapeuticAreas":["Cardiovascular"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"AMOSULALOL","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Amosulalol is a small molecule drug in the amosulalol class, but its target and approved indications are unknown. Its bioavailability is high at 99%. The commercial status of amosulalol is unclear, with unknown generic manufacturers and patent status. Further information on its pharmacokinetics, such as half-life, is also unavailable. As a result, key safety considerations and clinical use cannot be fully assessed.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}