{"id":"amniotic-suspension-allograft","brandName":"Amniotic Suspension Allograft","genericName":"Amniotic Suspension Allograft","companyId":"organogenesis","companyName":"Organogenesis","phase":"phase_3","status":"active","modality":"Biologic","aliases":["Rheo, Flowgraft"],"developmentCodes":[],"firstApprovalDate":null,"firstApprovalCountry":null,"aiSummary":"Amniotic Suspension Allograft is a protein-based treatment that functions as an insulin receptor agonist. It has been studied as a potential treatment for conditions such as knee osteoarthritis, knee osteoarthristis, and rotator cuff tears through injections of 20 mg or 40 mg of the allograft.","enrichmentLevel":3,"visitCount":1,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This biologic product contains viable and non-viable amniotic cells, growth factors, and extracellular matrix components derived from donated amniotic membrane. It is designed to modulate the inflammatory response, promote angiogenesis, and support tissue regeneration at the site of application. The allograft provides a biological scaffold and bioactive factors that facilitate wound healing and tissue remodeling.","oneSentence":"Amniotic Suspension Allograft delivers amniotic membrane-derived cells and proteins to promote tissue repair and reduce inflammation.","_ai_confidence":"medium"},"administration":{},"safety":{"commonSideEffects":[{"rate":null,"effect":"Infection at application site"},{"rate":null,"effect":"Allergic reaction"},{"rate":null,"effect":"Delayed wound healing"}]},"trials":[],"indications":{"approved":[{"name":"Diabetic foot ulcers"},{"name":"Chronic wounds"},{"name":"Surgical wounds"}]},"commercial":null,"patents":[],"timeline":[],"rwe":[],"competitors":[],"ownershipHistory":[],"trialDetails":[],"genericFilers":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"labelChanges":[],"nice":null,"revenue":null,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":false,"score":3}}