{"id":"amniogen","safety":{"commonSideEffects":[{"rate":null,"effect":"Infection at application site"},{"rate":null,"effect":"Allergic reaction"},{"rate":null,"effect":"Local inflammation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The product is derived from processed amniotic membrane tissue, which contains naturally occurring growth factors, cytokines, and extracellular matrix components. These bioactive molecules facilitate wound healing, reduce inflammation, and promote cellular regeneration when applied topically or injected. The mechanism leverages the inherent regenerative properties of amniotic tissue to support tissue repair in various clinical applications.","oneSentence":"AMNIOGEN is an amniotic membrane-derived biological product that promotes tissue repair and regeneration through growth factors and anti-inflammatory signaling.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:26:21.924Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Wound healing and tissue repair"},{"name":"Burn treatment"},{"name":"Chronic wounds"}]},"trialDetails":[{"nctId":"NCT06704893","phase":"PHASE3","title":"Amniotic Suspension Allograft Injection for Knee Osteoarthritis","status":"RECRUITING","sponsor":"Chang Gung Memorial Hospital","startDate":"2024-10-21","conditions":"Knee, Osteoarthritis","enrollment":160},{"nctId":"NCT04698265","phase":"NA","title":"Efficacy of Intra-articular Injection of Human Amniotic Suspension Allograft and Platelet-rich Plasma in the Treatment of Knee Osteoarthritis.","status":"UNKNOWN","sponsor":"Kaohsiung Veterans General Hospital.","startDate":"2021-01-01","conditions":"Knee Osteoarthristis","enrollment":150},{"nctId":"NCT04599673","phase":"PHASE4","title":"Prospective Analysis of Intraoperative AMNIOGEN® Injection in Patients With Rotator Cuff Tear","status":"UNKNOWN","sponsor":"Kaohsiung Veterans General Hospital.","startDate":"2020-10-15","conditions":"Rotator Cuff Tears","enrollment":100}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"AMNIOGEN","genericName":"AMNIOGEN","companyName":"Kaohsiung Veterans General Hospital.","companyId":"kaohsiung-veterans-general-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"AMNIOGEN is an amniotic membrane-derived biological product that promotes tissue repair and reduces inflammation. Used for Wound healing and tissue repair, Ocular surface disease, Burn and trauma wound management.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}