{"id":"amnioexcel-dressing-and-compression-therapy","safety":{"commonSideEffects":[{"rate":null,"effect":"Infection at wound site"},{"rate":null,"effect":"Allergic reaction"},{"rate":null,"effect":"Delayed wound healing"}]},"_chembl":{"chemblId":"CHEMBL1628401","moleculeType":"Small molecule","molecularWeight":"657.81"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"AmnioExCel contains bioactive proteins, growth factors, and extracellular matrix components derived from amniotic tissue that facilitate wound healing, angiogenesis, and tissue regeneration. When used with compression therapy, it creates an optimal microenvironment for wound closure while reducing edema and improving blood flow to promote faster epithelialization and tissue repair.","oneSentence":"AmnioExCel is an amniotic membrane-derived wound dressing that promotes tissue healing and reduces inflammation when combined with compression therapy for chronic wounds.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:21:39.196Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Chronic wounds (diabetic foot ulcers, venous leg ulcers, pressure ulcers)"},{"name":"Acute and traumatic wounds"}]},"trialDetails":[{"nctId":"NCT02929056","phase":"PHASE4","title":"Amniotic Membrane Allograft Application in the Management of Venous Leg Ulcerations","status":"TERMINATED","sponsor":"Prisma Health-Upstate","startDate":"2017-02-15","conditions":"Varicose Ulcer, Venous Insufficiency","enrollment":2},{"nctId":"NCT03547635","phase":"NA","title":"AMNIOEXCEL® Plus vs A Marketed Comparator vs SOC in the Management of Diabetic Foot Ulcers","status":"COMPLETED","sponsor":"Integra LifeSciences Corporation","startDate":"2018-05-03","conditions":"Diabetic Foot Ulcer","enrollment":116}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"AmnioExCel dressing and compression therapy","genericName":"AmnioExCel dressing and compression therapy","companyName":"Prisma Health-Upstate","companyId":"prisma-health-upstate","modality":"Biologic","firstApprovalDate":"","aiSummary":"AmnioExCel is an amniotic membrane-derived wound dressing that promotes tissue healing and reduces inflammation when combined with compression therapy for chronic wounds. Used for Chronic wounds (diabetic foot ulcers, venous leg ulcers, pressure ulcers), Acute and traumatic wounds.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}