{"id":"amlodipine-fa-tablet-high-dose-group","safety":{"commonSideEffects":[{"rate":"null","effect":"Edema"},{"rate":"null","effect":"Dizziness"},{"rate":"null","effect":"Headache"}]},"_chembl":{"chemblId":"CHEMBL1200402","moleculeType":"Small molecule","molecularWeight":"567.06"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This results in decreased peripheral resistance and a subsequent decrease in blood pressure. Amlodipine-FA tablet is a calcium channel blocker, which is a class of medications that work by blocking the influx of calcium ions into smooth muscle cells, leading to vasodilation and reduced blood pressure.","oneSentence":"Amlodipine-FA tablet works by inhibiting the L-type calcium channels in smooth muscle cells, leading to vasodilation and reduced blood pressure.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T04:08:54.515Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hypertension"},{"name":"Angina pectoris"}]},"trialDetails":[{"nctId":"NCT01956786","phase":"PHASE2, PHASE3","title":"Efficacy of Amlodipine-Folic Acid Tablets on Reduction of Blood Pressure and Plasma Homocysteine","status":"UNKNOWN","sponsor":"Shenzhen Ausa Pharmed Co.,Ltd","startDate":"2013-09","conditions":"Essential Hypertension","enrollment":540},{"nctId":"NCT01848873","phase":"PHASE2, PHASE3","title":"Efficacy of Amlodipine-folic Acid Tablets on Reduction of Blood Pressure and Plasma Homocysteine","status":"UNKNOWN","sponsor":"Shenzhen Ausa Pharmed Co.,Ltd","startDate":"2013-01","conditions":"Essential Hypertension","enrollment":756}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["high dose"],"phase":"phase_2","status":"active","brandName":"Amlodipine-FA tablet,high dose group","genericName":"Amlodipine-FA tablet,high dose group","companyName":"Shenzhen Ausa Pharmed Co.,Ltd","companyId":"shenzhen-ausa-pharmed-co-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Amlodipine-FA tablet works by inhibiting the L-type calcium channels in smooth muscle cells, leading to vasodilation and reduced blood pressure. Used for Hypertension, Angina pectoris.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}