{"id":"amisometradine","rwe":[{"pmid":"13840955","year":"1960","title":"A uracil diuretic: amisometradine (rolicton).","finding":"","journal":"Archives internationales de pharmacodynamie et de therapie","studyType":"Clinical Study"},{"pmid":"13651512","year":"1959","title":"Amisometradine (rolicton) in the treatment of congestive heart failure.","finding":"","journal":"British heart journal","studyType":"Clinical Study"},{"pmid":"13659079","year":"1959","title":"[Comparative study of the diuretic effect of a mercurial, chlorothiazide & amisometradine].","finding":"","journal":"La Semana medica","studyType":"Clinical Study"},{"pmid":"13627415","year":"1959","title":"Observations on the prolonged administration of amisometradine.","finding":"","journal":"American practitioner and digest of treatment","studyType":"Clinical Study"},{"pmid":"13489295","year":"1958","title":"Amisometradine, a new oral diuretic.","finding":"","journal":"British medical journal","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"amisometradin","offLabel":[],"synonyms":["amisometradine","aminoisometradin","aminoisometradine","amisometradin"],"timeline":[],"brandName":"Amisometradin","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells have locks on them, and amisometradin is a key that fits into one of those locks. When it binds to the lock, it triggers a series of events that help to treat a particular condition. This is a simplified explanation of how amisometradin works at a molecular level.","oneSentence":"Amisometradin works by interacting with a specific molecular target to produce a therapeutic effect.","technicalDetail":"Amisometradin's exact mechanism of action is unknown, but it is believed to interact with a specific molecular target to produce its therapeutic effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3671","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=AMISOMETRADINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:42:04.901277","biosimilars":[],"competitors":[],"genericName":"amisometradine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"002317","UNII":"30973N61ZF","CHEBI":"CHEBI:134852","INN_ID":"650","UMLSCUI":"C0301545","ChEMBL_ID":"CHEMBL2105979","PUBCHEM_CID":"11071","SNOMEDCT_US":"39263003"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":6,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"1960 Jul 1","pmid":"13840955","title":"A uracil diuretic: amisometradine (rolicton).","journal":"Archives internationales de pharmacodynamie et de therapie"},{"date":"1959 Apr","pmid":"13651512","title":"Amisometradine (rolicton) in the treatment of congestive heart failure.","journal":"British heart journal"},{"date":"1959 Mar 26","pmid":"13659079","title":"[Comparative study of the diuretic effect of a mercurial, chlorothiazide & amisometradine].","journal":"La Semana medica"},{"date":"1959 Mar","pmid":"13627415","title":"Observations on the prolonged administration of amisometradine.","journal":"American practitioner and digest of treatment"},{"date":"1958 Jan 4","pmid":"13489295","title":"Amisometradine, a new oral diuretic.","journal":"British medical journal"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Amisometradin is a small molecule. It is also known by the synonyms Amisometradina, Amisometradine, and NSC-70479.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}