{"id":"amiphenazole","rwe":[{"pmid":"29748782","year":"2018","title":"Stereoselective synthesis, X-ray analysis, computational studies and biological evaluation of new thiazole derivatives as potential anticancer agents.","finding":"","journal":"Chemistry Central journal","studyType":"Clinical Study"},{"pmid":"8363028","year":"1993","title":"[Continuous monitoring of spontaneous respiration in the postoperative phase. 4. The effect of postoperative pain therapy on cutaneous oxygen and carbon dioxide partial pressure following gynecologic surgery with neuroleptanalgesia].","finding":"","journal":"Der Anaesthesist","studyType":"Clinical Study"},{"pmid":"8488994","year":"1993","title":"[Continuous monitoring of spontaneous postoperative respiration. 3. The effect of amiphenazole on cutaneous oxygen and carbon dioxide partial pressure following gynecologic surgery under halothane anesthesia].","finding":"","journal":"Der Anaesthesist","studyType":"Clinical Study"},{"pmid":"1350432","year":"1992","title":"[Development of continuous monitoring of spontaneous respiration in the postoperative phase. 2. Cutaneous oxygen and carbon dioxide partial pressures following i.v. bolus application of fentanyl, buprenorphine, naloxone and amiphenazole in healthy adult subjects].","finding":"","journal":"Der Anaesthesist","studyType":"Clinical Study"},{"pmid":"6994518","year":"1980","title":"Antagonists of morphine-induced respiratory depression. A study in postoperative patients.","finding":"","journal":"Anaesthesia","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Respiratory System Agents","category":"pharmacology"}],"phase":"phase_2","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"amphisol","offLabel":[],"synonyms":["amiphenazole","amifenazol","amifenazole","amiphenazol","amphisol","daftazol","daptazile","daptazole","fenamizol","phenamizol","phenamizole"],"timeline":[],"brandName":"Amphisol","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine Amphisol as a key that fits into a lock on a cell. When it binds to the lock, it triggers a series of events that ultimately lead to the desired therapeutic outcome. This process can involve changes in the way cells communicate with each other or the way they respond to signals.","oneSentence":"Amphisol is a small molecule that works by interacting with a specific biological target to produce a therapeutic effect.","technicalDetail":"Amphisol's mechanism of action is not well-characterized, but it is believed to involve the modulation of a specific biological pathway or receptor. Further research is needed to fully understand its pharmacological properties and potential clinical applications."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/177","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=AMIPHENAZOLE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:41:22.913041","biosimilars":[],"competitors":[],"genericName":"amiphenazole","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"7ZJ8PWY0XD","CHEBI":"CHEBI:134843","INN_ID":"510","UMLSCUI":"C0051684","ChEMBL_ID":"CHEMBL1514085","PUBCHEM_CID":"10275","SNOMEDCT_US":"7975001","MESH_SUPPLEMENTAL_RECORD_UI":"C004484"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2018 May 11","pmid":"29748782","title":"Stereoselective synthesis, X-ray analysis, computational studies and biological evaluation of new thiazole derivatives as potential anticancer agents.","journal":"Chemistry Central journal"},{"date":"1993 Jul","pmid":"8363028","title":"[Continuous monitoring of spontaneous respiration in the postoperative phase. 4. The effect of postoperative pain therapy on cutaneous oxygen and carbon dioxide partial pressure following gynecologic surgery with neuroleptanalgesia].","journal":"Der Anaesthesist"},{"date":"1993 Apr","pmid":"8488994","title":"[Continuous monitoring of spontaneous postoperative respiration. 3. The effect of amiphenazole on cutaneous oxygen and carbon dioxide partial pressure following gynecologic surgery under halothane anesthesia].","journal":"Der Anaesthesist"},{"date":"1992 Apr","pmid":"1350432","title":"[Development of continuous monitoring of spontaneous respiration in the postoperative phase. 2. Cutaneous oxygen and carbon dioxide partial pressures following i.v. bolus application of fentanyl, buprenorphine, naloxone and amiphenazole in healthy adult subjects].","journal":"Der Anaesthesist"},{"date":"1980 Jan","pmid":"6994518","title":"Antagonists of morphine-induced respiratory depression. A study in postoperative patients.","journal":"Anaesthesia"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Amphisol is a small molecule with synonyms including Amifenasol, Amiphénazol, and Amiphénazole.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}