{"id":"aminohydroxybutyric-acid","rwe":[{"pmid":"6244218","year":"1980","title":"Stimulatory effects of gamma-aminohydroxybutyric acid (GABOB) on growth hormone, prolactin and cortisol release in man.","finding":"","journal":"Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme","studyType":"Clinical Study"},{"pmid":"5760910","year":"1968","title":"[Use of the sodium salt of gamma-aminohydroxybutyric acid during Cesarean section].","finding":"","journal":"Akusherstvo i ginekologiia","studyType":"Clinical Study"},{"pmid":"5585845","year":"1967","title":"[Detection and isolation of canaline (2-amino-4-aminohydroxybutyric acid)].","finding":"","journal":"Die Naturwissenschaften","studyType":"Clinical Study"}],"tags":[{"label":"aminohydroxybutyric acid","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Epilepsy","category":"indication"}],"phase":"unknown","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"gabob","offLabel":[],"synonyms":["gamma-Amino-beta-hydroxybutyric acid","gabob","gabomade","gaboril","alpha-Hydroxy-GABA","gamibetal","beta-Hydroxy-GABA","buxamine","3-Hydroxy-GABA","aminohydroxybutyric acid"],"timeline":[],"brandName":"Gabob","ecosystem":[{"indication":"Epilepsy","otherDrugs":[{"name":"amobarbital","slug":"amobarbital","company":""},{"name":"carbamazepine","slug":"carbamazepine","company":"Novartis"},{"name":"diazepam","slug":"diazepam","company":"Roche"},{"name":"felbamate","slug":"felbamate","company":"Meda Pharms"}],"globalPrevalence":50000000}],"mechanism":{"modality":"Small Molecule","drugClass":"aminohydroxybutyric acid","explanation":"Imagine your brain is a city with many different streets and intersections. Gabob helps to calm down the traffic on these streets by reducing the activity of certain chemical messengers, or neurotransmitters, that can cause seizures. This helps to prevent seizures from occurring.","oneSentence":"Gabob is thought to work by modulating the activity of certain neurotransmitters in the brain.","technicalDetail":"The exact mechanism of action of Gabob is unknown, but it is believed to involve the modulation of GABA receptors and other ion channels in the brain."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/1263","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=aminohydroxybutyric acid","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:41:06.135567","biosimilars":[],"competitors":[],"genericName":"aminohydroxybutyric acid","indications":{"approved":[{"name":"Epilepsy","source":"DrugCentral","snomedId":84757009,"regulator":"FDA","usPrevalence":3400000,"globalPrevalence":50000000,"prevalenceMethod":"curated","prevalenceSource":"WHO, 2023"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"006167","UNII":"1ZHM019FLD","CHEBI":"CHEBI:74821","RXNORM":"236512","UMLSCUI":"C0771792","ChEMBL_ID":"CHEMBL93515","KEGG_DRUG":"D00174","DRUGBANK_ID":"DB15985","PUBCHEM_CID":"2149"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":3,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[{"date":"1980 Jan","pmid":"6244218","title":"Stimulatory effects of gamma-aminohydroxybutyric acid (GABOB) on growth hormone, prolactin and cortisol release in man.","journal":"Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme"},{"date":"1968 Jul","pmid":"5760910","title":"[Use of the sodium salt of gamma-aminohydroxybutyric acid during Cesarean section].","journal":"Akusherstvo i ginekologiia"},{"date":"1967 Apr","pmid":"5585845","title":"[Detection and isolation of canaline (2-amino-4-aminohydroxybutyric acid)].","journal":"Die Naturwissenschaften"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Gabob, also known as aminohydroxybutyric acid, is a small molecule drug in the aminohydroxybutyric acid class. Its exact mechanism of action is unknown, but it is FDA-approved for the treatment of epilepsy. The commercial status of Gabob is unclear, and it is not known whether it is patented or available as a generic medication. Further research is needed to fully understand the safety and efficacy of Gabob. As a result, key safety considerations are not well established.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}