{"id":"amfecloral","rwe":[],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"acutran","offLabel":[],"synonyms":["amfecloral","amphecloral","acutran"],"timeline":[],"brandName":"Acutran","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body has a stress response system that helps you react to danger. Acutran may help regulate this system, reducing the negative effects of stress on the body. This could potentially help alleviate symptoms of stress-related conditions.","oneSentence":"Acutran is thought to work by influencing the body's stress response and possibly modulating the hypothalamic-pituitary-adrenal axis.","technicalDetail":"Acutran is believed to exert its effects through interaction with the hypothalamic-pituitary-adrenal axis, potentially influencing the release of stress hormones such as cortisol and adrenaline."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Amfecloral","title":"Amfecloral","extract":"Amfecloral (INN) or amphecloral (USAN) is a combination drug containing a central nervous system (CNS) stimulant and anorectic drug, dextroamphetamine, as well as a CNS depressant and sedative-hypnotic, chloral hydrate."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/5113","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=amfecloral","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Amfecloral","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T08:40:09.049006","biosimilars":[],"competitors":[],"genericName":"amfecloral","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"6015XOA0BI","CHEBI":"CHEBI:135924","INN_ID":"1207","UMLSCUI":"C0301353","ChEMBL_ID":"CHEMBL2105544","KEGG_DRUG":"D02926","DRUGBANK_ID":"DB08924","PUBCHEM_CID":"21759","SNOMEDCT_US":"14796007"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Nephrology"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Acutran is a combination drug containing dextroamphetamine, a central nervous system stimulant, and chloral hydrate, a central nervous system depressant and sedative-hypnotic.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}