{"id":"ambazone","rwe":[{"pmid":"41809797","year":"2026","title":"Systematic analysis of UBE2D3 and its association with prognosis, tumor microenvironment, and drug sensitivity in renal clear cell carcinoma.","finding":"","journal":"Translational andrology and urology","studyType":"Clinical Study"},{"pmid":"41405593","year":"2025","title":"[Combined use of Ketoprofen solution and Faryngazon antiseptic in dentistry].","finding":"","journal":"Stomatologiia","studyType":"Clinical Study"},{"pmid":"26633377","year":"2015","title":"Repositioning of Thiourea-Containing Drugs as Tyrosinase Inhibitors.","finding":"","journal":"International journal of molecular sciences","studyType":"Clinical Study"},{"pmid":"25187325","year":"2014","title":"Crystal structure and physicochemical characterization of ambazone monohydrate, anhydrous, and acetate salt solvate.","finding":"","journal":"Journal of pharmaceutical sciences","studyType":"Clinical Study"},{"pmid":"18441955","year":"2007","title":"[Microbial sensitivity to ambazone (Faringosept) in pharyngeal samples from patients with acute infections of the upper respiratory tract].","finding":"","journal":"Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990)","studyType":"Clinical Study"}],"tags":[{"label":"ambazone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"R02AA01","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"ivertol","offLabel":[],"synonyms":["ambazone","faringosept","1,4-benzoquinone amidinohydrazone thiosemicarbazone","inversal","ivertol"],"timeline":[],"brandName":"Ivertol","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"ambazone","explanation":"Imagine a key fitting into a lock - Ivertol is like a key that binds to a specific lock on a cell, but we don't know what that lock does yet. This binding action can help to either block or enhance a particular process in the body, but the details are still unclear.","oneSentence":"Ivertol works by binding to a specific target, but the exact target is unknown.","technicalDetail":"Ivertol's mechanism of action involves binding to a specific protein or receptor, but the exact molecular details and the resulting downstream effects are not well understood."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/145","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=AMBAZONE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:40:03.324406","biosimilars":[],"competitors":[{"drugName":"chlorhexidine","drugSlug":"chlorhexidine","fdaApproval":"1976-09-17","patentExpiry":"Oct 2, 2027","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"cetylpyridinium","drugSlug":"cetylpyridinium","fdaApproval":"","relationship":"same-class"},{"drugName":"benzethonium","drugSlug":"benzethonium","fdaApproval":"","relationship":"same-class"},{"drugName":"hexylresorcinol","drugSlug":"hexylresorcinol","fdaApproval":"","relationship":"same-class"},{"drugName":"oxyquinoline","drugSlug":"oxyquinoline","fdaApproval":"","relationship":"same-class"},{"drugName":"povidone-iodine","drugSlug":"povidone-iodine","fdaApproval":"1985-11-29","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"benzalkonium","drugSlug":"benzalkonium","fdaApproval":"","relationship":"same-class"},{"drugName":"phenol","drugSlug":"phenol","fdaApproval":"","relationship":"same-class"}],"genericName":"ambazone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"chlorhexidine","brandName":"chlorhexidine","genericName":"chlorhexidine","approvalYear":"1976","relationship":"same-class"},{"drugId":"cetylpyridinium","brandName":"cetylpyridinium","genericName":"cetylpyridinium","approvalYear":"","relationship":"same-class"},{"drugId":"benzethonium","brandName":"benzethonium","genericName":"benzethonium","approvalYear":"","relationship":"same-class"},{"drugId":"hexylresorcinol","brandName":"hexylresorcinol","genericName":"hexylresorcinol","approvalYear":"","relationship":"same-class"},{"drugId":"oxyquinoline","brandName":"oxyquinoline","genericName":"oxyquinoline","approvalYear":"","relationship":"same-class"},{"drugId":"povidone-iodine","brandName":"povidone-iodine","genericName":"povidone-iodine","approvalYear":"1985","relationship":"same-class"},{"drugId":"benzalkonium","brandName":"benzalkonium","genericName":"benzalkonium","approvalYear":"","relationship":"same-class"},{"drugId":"phenol","brandName":"phenol","genericName":"phenol","approvalYear":"","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"BYK4592A3Q","CHEBI":"CHEBI:134962","INN_ID":"822","UMLSCUI":"C0043983","ChEMBL_ID":"CHEMBL2103762","KEGG_DRUG":"D07376","DRUGBANK_ID":"DB13697","PUBCHEM_CID":"1549158"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"R02AA01","allCodes":["R02AA01"]},"biosimilarFilings":[],"recentPublications":[{"date":"2026 Feb 28","pmid":"41809797","title":"Systematic analysis of UBE2D3 and its association with prognosis, tumor microenvironment, and drug sensitivity in renal clear cell carcinoma.","journal":"Translational andrology and urology"},{"date":"2025","pmid":"41405593","title":"[Combined use of Ketoprofen solution and Faryngazon antiseptic in dentistry].","journal":"Stomatologiia"},{"date":"2015 Dec 2","pmid":"26633377","title":"Repositioning of Thiourea-Containing Drugs as Tyrosinase Inhibitors.","journal":"International journal of molecular sciences"},{"date":"2014 Nov","pmid":"25187325","title":"Crystal structure and physicochemical characterization of ambazone monohydrate, anhydrous, and acetate salt solvate.","journal":"Journal of pharmaceutical sciences"},{"date":"2007 Jan-Jun","pmid":"18441955","title":"[Microbial sensitivity to ambazone (Faringosept) in pharyngeal samples from patients with acute infections of the upper respiratory tract].","journal":"Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990)"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ivertol (AMBAZONE) is a small molecule drug in the ambazone class, but specific details about its development, approval status, and indications are not available. As a result, there is limited information about its commercial status, safety considerations, and pharmacokinetic properties. Further research is needed to understand the specifics of Ivertol. The exact target of Ivertol is also unknown. It is essential to consult reliable sources for accurate information about this drug.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}