{"id":"amanozine","rwe":[],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Cobalamin deficiency","category":"indication"},{"label":"Pernicious anemia","category":"indication"},{"label":"Prevention of Vitamin B12 Deficiency","category":"indication"}],"phase":"phase_2","safety":{"commonSideEffects":[],"contraindications":["Hypokalemia","Leber's optic atrophy"]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"urofort","offLabel":[],"synonyms":["amanozine","n-phenylformoguanamine","urofort"],"timeline":[],"brandName":"Urofort","ecosystem":[{"indication":"Cobalamin deficiency","otherDrugs":[{"name":"cobalamin","slug":"cobalamin","company":""},{"name":"cyanocobalamin","slug":"cyanocobalamin","company":""},{"name":"hydroxocobalamin","slug":"hydroxocobalamin","company":"Watson Labs"},{"name":"thiamine","slug":"thiamine","company":"Hospira"}],"globalPrevalence":null},{"indication":"Pernicious anemia","otherDrugs":[{"name":"cobalamin","slug":"cobalamin","company":""},{"name":"cyanocobalamin","slug":"cyanocobalamin","company":""},{"name":"hydroxocobalamin","slug":"hydroxocobalamin","company":"Watson Labs"},{"name":"thiamine","slug":"thiamine","company":"Hospira"}],"globalPrevalence":null},{"indication":"Prevention of Vitamin B12 Deficiency","otherDrugs":[{"name":"cobalamin","slug":"cobalamin","company":""},{"name":"cobamamide","slug":"cobamamide","company":""},{"name":"cyanocobalamin","slug":"cyanocobalamin","company":""},{"name":"folic acid","slug":"folic-acid","company":"Lederle"}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","explanation":"Think of Urofort like a supplement that helps your body get the Cobalamin it needs to make healthy red blood cells. Without enough Cobalamin, your body can't produce enough red blood cells, leading to anemia. Urofort helps fill this gap, supporting overall health and preventing related complications.","oneSentence":"Urofort works by providing a source of Cobalamin to the body, helping to address deficiencies and prevent related conditions.","technicalDetail":"Urofort is a small molecule modality that likely works by increasing the bioavailability of Cobalamin, allowing it to be absorbed and utilized by the body more effectively."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3667","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=AMANOZINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:39:30.024330","biosimilars":[],"competitors":[],"genericName":"amanozine","indications":{"approved":[{"name":"Cobalamin deficiency","source":"DrugCentral","snomedId":190634004,"regulator":"FDA"},{"name":"Pernicious anemia","source":"DrugCentral","snomedId":84027009,"regulator":"FDA"},{"name":"Prevention of Vitamin B12 Deficiency","source":"DrugCentral","snomedId":"","regulator":"FDA"}],"offLabel":[{"name":"Methylmalonic acidemia","source":"DrugCentral","drugName":"AMANOZINE","evidenceCount":0,"evidenceLevel":"emerging"}],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"X43W7JDA8L","CHEBI":"CHEBI:134833","INN_ID":"802","UMLSCUI":"C2698079","ChEMBL_ID":"CHEMBL13589","PDB_CHEM_ID":"7ZF","PUBCHEM_CID":"10832"},"formularyStatus":[],"_enricherVersion":"v2","_offLabelChecked":true,"developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Hematology"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Urofort (AMANOZINE) is a small molecule modality developed for the treatment of Cobalamin deficiency, Pernicious anemia, and Prevention of Vitamin B12 Deficiency. The current owner of Urofort is unknown. It is used to address deficiencies in Cobalamin, a crucial vitamin for the production of red blood cells. Urofort's commercial status is unclear, and its safety considerations are not well-documented. Further research is needed to fully understand its pharmacological properties and potential risks.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}