{"id":"aluminium-oxide","rwe":[],"tags":[{"label":"aluminium oxide","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"D10AX04","category":"atc"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"_fixedAt":"2026-03-30T16:30:58.857381","allNames":["aluminium oxide"],"offLabel":[],"synonyms":["aluminium oxide"],"timeline":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"aluminium oxide","explanation":"This helps to reduce heartburn and acid reflux symptoms by creating a protective barrier in the stomach. By neutralizing acid, aluminium oxide can help to heal damaged tissues in the esophagus and reduce discomfort. This can provide relief for people experiencing symptoms of gastroesophageal reflux disease (GERD).","oneSentence":"Aluminium oxide works by binding to and neutralizing excess stomach acid.","technicalDetail":"Aluminium oxide acts as an antacid by reacting with hydrochloric acid in the stomach to form aluminium chloride and water, thereby reducing gastric acidity."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Aluminium_oxide","title":"Aluminium oxide","extract":"Aluminium oxide (or aluminium(III) oxide) is a chemical compound of aluminium and oxygen with the chemical formula Al2O3. It is the most commonly occurring of several aluminium oxides, and specifically identified as aluminium oxide. It is commonly called alumina and may also be called aloxide, aloxite, ALOX or alundum in various forms and applications. Alumina is refined from bauxite. It occurs naturally in its crystalline polymorphic phase α-Al2O3 as the mineral corundum, varieties of which form the precious gemstones ruby and sapphire, which have an alumina content approaching 100%. Al2O3 is used as feedstock to produce aluminium metal, as an abrasive owing to its hardness, and as a refractory material owing to its high melting point.","wiki_history":"==History==\n\nThe field of aluminium oxide ceramics has a long history. Aluminium salts were widely used in ancient and medieval alchemy. Several vintage textbooks cover the history of the field."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4438","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=aluminium%20oxide","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=aluminium oxide","fields":["publications"],"source":"PubMed/NCBI"},{"id":4,"url":"https://en.wikipedia.org/wiki/Aluminium_oxide","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T08:39:04.082484","biosimilars":[],"competitors":[{"drugName":"aluminium chloride","drugSlug":"aluminium-chloride","fdaApproval":"","relationship":"same-class"},{"drugName":"resorcinol","drugSlug":"resorcinol","fdaApproval":"","relationship":"same-class"},{"drugName":"azelaic acid","drugSlug":"azelaic-acid","fdaApproval":"1995-09-13","patentExpiry":"Sep 18, 2027","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"dapsone","drugSlug":"dapsone","fdaApproval":"1979-07-03","patentExpiry":"Nov 18, 2033","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"clascoterone","drugSlug":"clascoterone","fdaApproval":"2020-08-26","patentExpiry":"Nov 20, 2028","patentStatus":"Patent protected","relationship":"same-class"}],"genericName":"aluminium oxide","indications":{"approved":[],"offLabel":[],"pipeline":[]},"_fixedFields":["pubmed(931)"],"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"aluminium-chloride","brandName":"aluminium chloride","genericName":"aluminium chloride","approvalYear":"","relationship":"same-class"},{"drugId":"resorcinol","brandName":"resorcinol","genericName":"resorcinol","approvalYear":"","relationship":"same-class"},{"drugId":"azelaic-acid","brandName":"azelaic acid","genericName":"azelaic acid","approvalYear":"1995","relationship":"same-class"},{"drugId":"dapsone","brandName":"dapsone","genericName":"dapsone","approvalYear":"1979","relationship":"same-class"},{"drugId":"clascoterone","brandName":"clascoterone","genericName":"clascoterone","approvalYear":"2020","relationship":"same-class"}],"trialDetails":[{"nctId":"NCT07366671","phase":"","title":"SAvvywire for Pacing and Procedural Hemodynamics In Transcatheter Aortic Valve Replacement Evaluation","status":"RECRUITING","sponsor":"dr Pim A.L. 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