{"id":"altrenogest","rwe":[],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Hormones","category":"pharmacology"},{"label":"Progestins","category":"pharmacology"}],"phase":"marketed","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=ALTRENOGEST","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-19T23:27:43.613265+00:00"},"timeline":{"url":"https://en.wikipedia.org/wiki/Altrenogest","method":"deterministic","source":"Wikipedia","rawText":"","confidence":0.8,"sourceType":"wikipedia","retrievedAt":"2026-04-19T23:27:51.381720+00:00"},"aiSummary":{"url":"","method":"ai_extraction","source":"AI Strategic Summary","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"ai_extraction","retrievedAt":"2026-04-19T23:28:00.292271+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-19T23:27:49.842292+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ALTRENOGEST","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-19T23:27:50.226411+00:00"},"crossReferences.chemblId":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL1315492/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-19T23:27:51.028111+00:00"}},"allNames":"allyltrenbolone","offLabel":[],"synonyms":["altrenogest","A-35957","NSC-759180","allyltrenbolone"],"timeline":[],"aiSummary":"ALTRENOGEST, an allyltrenbolone-based drug, is currently on the market with a key composition patent expiring in 2028. The drug's mechanism of interacting with specific receptors in the body provides a unique therapeutic approach. The primary risk is the lack of clear revenue data and key trial results, which may impact investor confidence and market positioning.","brandName":"Allyltrenbolone","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"","oneSentence":"","technicalDetail":"Allyltrenbolone is a synthetic steroid that is thought to interact with androgen receptors, potentially influencing gene expression and cellular function."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Altrenogest","title":"Altrenogest","extract":"Altrenogest, sold under the brand names Swinemate and Altren manufactured by Aurora Pharmaceutical and Regumate manufactured by Merck, is a progestin of the 19-nortestosterone group which is widely used in veterinary medicine to suppress or synchronize estrus in horses and pigs. It is available for veterinary use in both Europe and the United States.","wiki_history":"==History==\nAltrenogest has been marketed as Regumate since the early 1980s.","wiki_society_and_culture":"==Society and culture==\n\n===Generic names===\nAltrenogest is the generic name of the drug and its , , and , while altrénogest is its .\n\n===Brand names===\nAltrenogest is marketed under the brand names Regumate and Matrix among others."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/5671","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ALTRENOGEST","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Altrenogest","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T08:38:52.184820","_validation":{"fieldsValidated":1,"lastValidatedAt":"2026-04-19T23:28:00.292520+00:00","fieldsConflicting":1,"overallConfidence":0.8},"biosimilars":[],"competitors":[],"genericName":"altrenogest","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"017828","UNII":"2U0X0JA2NB","INN_ID":"5075","RXNORM":"1314612","UMLSCUI":"C0102819","chemblId":"CHEMBL1315492","ChEMBL_ID":"CHEMBL1315492","KEGG_DRUG":"D02840","DRUGBANK_ID":"DB11372","PUBCHEM_CID":"10041070","SNOMEDCT_US":"419841009","MESH_SUPPLEMENTAL_RECORD_UI":"C023445"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":250,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","enrichmentLevel":3,"visitCount":2,"regulatoryByCountry":[{"country_code":"CA","regulator":"Health Canada","status":"approved","approval_date":null,"mah":"","brand_name_local":"","application_number":""},{"country_code":"US","regulator":"FDA","status":"approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null}],"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":1,"lastValidatedAt":"2026-04-19T23:28:00.292520+00:00","fieldsConflicting":1,"overallConfidence":0.8},"verificationStatus":"enriching","dataCompleteness":{"mechanism":false,"indications":false,"safety":false,"trials":false,"score":0}}